Crystal structure of a salt complex between (<Emphasis Type="Italic">S</Emphasis>)-2-(2′-methylbenzyl)succinic acid and (<Emphasis Type="Italic">R</Emphasis>)-1-phenylethylamine |
| |
| Authors: | Yu-min Liu Yong-qi Hu He Liu |
| |
| Institution: | (1) Department of Catalysis Science and Technology, School of Chemical Engineering and Technology, Tianjin University, Tianjin, 300072, P.R. China;(2) College of Chemical and Pharmaceutical Engineering, Hebei University of Science and Technology, Shijiazhuang, 050016, P.R. China;(3) No. 7 Department, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850, P.R. China |
| |
| Abstract: | The optically pure 2-(2′-methylbenzyl)succinic acid were obtained by the optical resolution of the racemates with the chiral
host 1-phenylethylamine. The structure of the salt complex between (S)-2-(2′-methylbenzyl)succinic acid and (R)-1-phenylethylamine was first elucidated by X-ray analysis: Monoclinic, Space group P21 with a=6.0781(12) ?, b=8.8224(18) ?, c=17.675(4) ?, β=97.64(3)°, V=939.4(3) ?3, Z=2, the absolute structure parameter is 0 (9). The crystal structure indicates that the hydrogen bonds are formed between
the acetate anions and the protonated amino group. The intermolecular hydrogen bond links the salt complex into a quasi-two-dimentional
netlike structure. |
| |
| Keywords: | Crystal structure resolution hydrogen bond |
| 本文献已被 SpringerLink 等数据库收录！ |
|
