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An efficient three-component synthesis of new barbiturate salts
Authors:Somayeh Ahadi  Maryam Abaszadeh  Hamid Reza Khavasi  Ayoob Bazgir
Institution:Department of Chemistry, Shahid Beheshti University, General Campus, Tehran 1983963113, Iran
Abstract:An efficient synthesis of new barbiturate salts consist of 2-aminopyridinium moiety by a?n uncatalyzed three-component condensation reaction of C–H acids, pyrimidine-tetraones, and 2-aminopyridines? in refluxing chloroform is reported. The reaction of pyrimidine-tetraones and 2-aminopyridines with ninhydrin in the formation of new barbiturate salts consist of 2-aminopyridinium moiety is also investigated.
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