Synthesis of benzoxazine and 1,3-oxazine derivatives via ligand-free copper(I)-catalyzed one-pot cascade addition/cyclization reaction |
| |
| Authors: | Guodong Shen Dingben Chen Yiliang Zhang Manman Sun Kai Chen Cong Jin Kaining Li Weiliang Bao |
| |
| Affiliation: | 1. Department of Chemistry, Xi Xi Campus, Zhejiang University, Hangzhou, Zhejiang 310028, PR China;2. College of Pharmaceutical and Chemical Engineering, Taizhou University, Linhai 317000, Zhejiang, PR China |
| |
| Abstract: | A novel and efficient synthesis of benzoxazine and 1,3-oxazine derivatives via ligand-free copper(I)-catalyzed one-pot cascade addition/cyclization reaction has been developed. A variety of carbodiimides coupled with o-halophenylmethanols and/or substituted (Z)-3-iodoprop-2-en-1-ols to give the corresponding products in moderate to excellent yields under the mild condition. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
