Formal synthesis of TMC-69-6H via a one-pot enantioselective domino proline-mediated aldol/olefin homologation procedure |
| |
| Authors: | Sophie Vuong Nicolas Brondel Christophe Len Sébastien Papot Brigitte Renoux |
| |
| Affiliation: | Laboratoire “Synthèse et Réactivité des Substances Naturelles”, Université de Poitiers, UMR-CNRS 6514, 4 rue Michel Brunet, BP 633, 86022 Poitiers, France |
| |
| Abstract: | Enantioselective synthesis of TMC-69-6H was accomplished from readily accessible pyridone derivative via a domino proline-mediated aldol reaction/olefin homologation, followed by tandem ring-closing and cross metathesis. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
