Phomactins K–M,three novel phomactin-type diterpenes from a marine-derived fungus |
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Authors: | Masahiro Ishino Kaoru Kinoshita Kunio Takahashi Takashi Sugita Motoo Shiro Kimiko Hasegawa Kiyotaka Koyama |
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Institution: | 1. Departments of Pharmacognosy and Phytochemistry, Meiji Pharmaceutical University, Noshio 2-522-1, Kiyose-shi, Tokyo 204-8588, Japan;2. Departments of Microbiology, Meiji Pharmaceutical University, Noshio 2-522-1, Kiyose-shi, Tokyo 204-8588, Japan;3. X-ray Research Laboratory, Rigaku Corporation, Matsubara-cho 3-9-12, Akishima-shi, Tokyo 196-8666, Japan |
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Abstract: | Three novel diterpenes, phomactins K–M (1–3), were isolated from the cultures of an unidentified marine-derived fungus. The structures of 1–3 were elucidated from spectroscopic data (NMR, MS, IR), and the absolute configurations of 1, 2, and the relative configuration of 3 were determined by X-ray diffraction analysis. |
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