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Phomactins K–M,three novel phomactin-type diterpenes from a marine-derived fungus
Authors:Masahiro Ishino  Kaoru Kinoshita  Kunio Takahashi  Takashi Sugita  Motoo Shiro  Kimiko Hasegawa  Kiyotaka Koyama
Institution:1. Departments of Pharmacognosy and Phytochemistry, Meiji Pharmaceutical University, Noshio 2-522-1, Kiyose-shi, Tokyo 204-8588, Japan;2. Departments of Microbiology, Meiji Pharmaceutical University, Noshio 2-522-1, Kiyose-shi, Tokyo 204-8588, Japan;3. X-ray Research Laboratory, Rigaku Corporation, Matsubara-cho 3-9-12, Akishima-shi, Tokyo 196-8666, Japan
Abstract:Three novel diterpenes, phomactins K–M (13), were isolated from the cultures of an unidentified marine-derived fungus. The structures of 13 were elucidated from spectroscopic data (NMR, MS, IR), and the absolute configurations of 1, 2, and the relative configuration of 3 were determined by X-ray diffraction analysis.
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