A novel one-pot isocyanide-based four-component reaction: synthesis of highly functionalized 1H-pyrazolo[1,2-b]phthalazine-1,2-dicarboxylates and 1H-pyrazolo[1,2-a]pyridazine-1,2-dicarboxylates |
| |
Authors: | Sajjad Keshipour Salman Shojaei Ahmad Shaabani |
| |
Institution: | Department of Chemistry, Shahid Beheshti University, G.C., P.O. Box 19396-4716, Tehran, Iran |
| |
Abstract: | A new protocol has been developed for the efficient synthesis of structurally diverse 1H-pyrazolo1,2-b]phthalazine-1,2-dicarboxylates and 1H-pyrazolo1,2-a]pyridazine-1,2-dicarboxylates via a four-component reaction of hydrazine hydrate, dialkyl acetylenedicarboxylates, isocyanides and various cyclic anhydrides such as succinic anhydride, maleic anhydride and phthalic anhydride in ethanol/acetone (1:1) at room temperature in good to moderate yields. |
| |
Keywords: | |
本文献已被 ScienceDirect 等数据库收录! |
|