Synthesis of 6H-isoindolo[2,1-a]indol-6-ones through a sequential copper-catalyzed C-N coupling and palladium-catalyzed C–H activation reaction |
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| Authors: | Hua-Feng He Sheng Dong Yi Chen Yang Yang Yueqin Le Weiliang Bao |
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| Institution: | Department of Chemistry, Xi Xi Campus, Zhejiang University, Hangzhou, Zhejiang 310028, PR China |
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| Abstract: | A series of 6H-isoindolo2,1-a]indol-6-ones were synthesized through one-pot sequential coupling reactions, which were comprised of a copper-catalyzed C–N coupling cyclization and a palladium-catalyzed C–H activation course. General chemicals benzoyl chlorides and o-gem-dibromovinyl anilines were employed as the starting substrates. |
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