Surface Modification of Intact Poly(dimethylsiloxane) for Cell Culture and Cell Migration

Cell migration plays a crucial role in various biological processes including embryogenests,wound healing,immune response,and tissue development~(1]).Exploring and understanding the mechanisms and related factors underlying cell migration arc also very important for emerging areas of biotedmology which focus on cellular transplantation and the manufacture of artificial tissues,as well as for the development of new therapeutic strategies for controlling invasive tumor cells~(2]).