Temperature-Insensitive Measurement of Glucose Concentration Based on Near Infrared Spectroscopy and Partial Least Squares Analysis |
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| Authors: | Hidenobu Arimoto Masatoshi Tarumi Yukio Yamada |
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| Affiliation: | (1) Institute of Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology, AIST Tsukuba East, Tsukuba, Ibaraki 305-8564, Japan;(2) Nikkiso Co., Ltd., 498-1 Shizutani, Haibara, Shizuoka 421-0496, Japan;(3) Department of Mechanical Engineering and Intelligent Systems, University of Electro-Communications, 1-5-1 Chofugaoka, Chofu, Tokyo 182-8585, Japan |
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| Abstract: | Temperature-insensitive partial least squares analysis for glucose measurement is presented based on Near Infrared spectroscopy in the wavelength range from 1,250 to 1,800nm. Experiments are performed using aqueous glucose solutions. To create a temperature-insensitive prediction model, the glucose concentration and water temperature are varied independently. The results of the predicted glucose concentration agree well with the actual glucose concentration with an error of 4.4%. |
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| Keywords: | blood glucose measurement non-invasive measurement multivariate analysis PLS NIR spectroscopy |
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