Cyclocondensation of 2-Aminobenzimidazole with Dimedone and Its Arylidene Derivatives |
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Authors: | V V Lipson S M Desenko S V Shishkina M G Shirobokova O V Shishkin V D Orlov |
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Institution: | (1) Ukraine Academy of Medical Sciences, V. Ya. Danilevsky Institute for Problems in Endocrine Pathology, Kharkov, 61002;(2) V. N. Karazin National University, Kharkov, 61077, Ukraine;(3) Institute of Single Crystals, Kharkov, 61001, Ukraine |
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Abstract: | The reactions of 2-aminobenzimidazole with substituted benzaldehydes and dimedone, 2-arylidene derivatives of dimedone, 9-arylhexahydro-1H-xanthene-1,8(2H)-diones and also with dimedone and DMF have been studied. The direction of formation of the pyrimidine ring has been established and discussed. An X-ray structural investigation of 2,2-dimethyl-2,3-dihydrobenzimidazo1,2-a]quinazolin-4(1H)-one has been carried out. |
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Keywords: | 2-aminobenzimidazole 2-arylidene derivatives of dimedone dimedone partially hydrogenated quinazoline systems X-ray structural analysis cyclocondensation |
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