Global Government applications of analogues,SAR s and QSAR s to predict aquatic toxicity,chemical or physical properties,environmental fate parameters and health effects of organic chemicals |
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| Authors: | JD Walker L Carlsen E Hulzebos B Simon-Hettich |
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| Institution: | 1. U.S. Environmental Protection Agency (7401M) , TSCA Interagency Testing Committee (ITC) , 1200 Pennsylvania Avenue, NW, Washington, DC, 20460, USA;2. Department of Environment, Technology and Social Studies , Roskilde University , Roskilde, DK-4000, Denmark;3. Center for Substances and Risk , National Institute for Public Health and the Environment , Bilthoven, The Netherlands;4. Institute of Toxicology , Merck KGaA , Darmstadt, D-64271, Germany |
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| Abstract: | Faced with the need to predict physical and chemical properties, environmental fate, ecological effects and health effects of organic chemicals in the absence of experimental data, several Government organizations have been applying analogues, Structure Activity Relationships (SARs) and Quantitative Structure Activity Relationships (QSARs) to develop those predictions. To establish some benchmarks for monitoring future increases in applications of analogues, SARs and QSARs by global Government organizations, this paper describes the current applications of analogues, SARs and QSARs by Australian, Canadian, Danish, European, German, Japanese, Netherlands, and United States Government organizations to predict physical and chemical properties, environmental fate, ecological effects and health effects of organic chemicals. |
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| Keywords: | Sars Qsars Government Effects Environmental Fate Physicochemical Properties |
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