Synthesis and Inclusion Properties of Macrocyclic Polyethers Containing Phosphonic Groups |
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| Authors: | Giuseppe A Consiglio Salvatore Failla Paolo Finocchiaro Mandana Visi Kenneth I Hardcastle |
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| Institution: | 1. Istituto Chimico, Facoltá di Ingegneria, Universitá di Catania , Viale A. Doria 6, I-95125, Catania, Italy;2. Department of Chemistry , California State University , 18111 Nordhoff Street, Northridge, CA, 91330-8262, USA |
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| Abstract: | Abstract Three novel polyether macrocycles II-IV bearing phosphonic groups have been synthesised in satisfactory yields. Macrocycle II was found to form a 1:1 inclusion compound with cyclohexane and thus was easily isolated from the reaction mixture as a clathrate. The crystal and molecular structure of the cyclohexane solvate has been determined by single crystal X-ray analyses and refined to an R of 0.028 for 3199 reflection. The compound is monoclinic, space group P21n with a = 15.886(6) Å, b = 11.657(5) Å, c = 18.621 (6) Å, β = 90.12(3)°, Z = 2. The whole molecule exhibits a great deal of disorder and the different conformations were modelled as consisting of two different primary conformers with population approximately 60:40. |
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| Keywords: | Polyethers phosphonic derivatives para-cyclo-phane inclusion formation synthetic routes |
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