| Asymmetric Baylis-Hillman Reaction between Chiral Activated Alkenes and Aromatic Aldehydes in Me3N/H2O/Solvent Medium |
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| 作者姓名： | Ke HE Zheng Hong ZHOU Hong Ying TANG Guo Feng ZHAO Chu Chi TANG |
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| 作者单位： | State Key Laboratory of Elemento-Organic Chemistry, Institute of Elemento-Organic Chemistry, Nankai University, Tianjin 300071 |
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| 基金项目： | We are grateful to the National Natural Science Foundation of China （20472033） and the Ph. D. Programs of Ministry of Education of China （No. 20020055002） for generous financial support for our programs. |
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| 摘 要： | Chiral activated alkene, L-menthyl acrylate and （＋）-N-α-phenylethyl acrylamide, induced asymmetric Baylis-HiUman reaction of aromatic aldehydes was realized at 25℃ for 7 days in Me3N/H2O/solvent homogeneous medium. The corresponding Baylis-Hillman adducts were obtained in good chemical yield with moderate to excellent diastereoselectivity （up to 99% de）.
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| 关 键 词： | 烯烃 手性拆合 活性化合物 不对称性 芳醛 溶剂 |
| 收稿时间： | 2005-01-26 |
Asymmetric Baylis-Hillman Reaction between Chiral Activated Alkenes and Aromatic Aldehydes in Me3N/H2O/Solvent Medium |
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| Ke HE Zheng Hong ZHOU Hong Ying TANG Guo Feng ZHAO Chu Chi TANG.Asymmetric Baylis-Hillman Reaction between Chiral Activated Alkenes and Aromatic Aldehydes in Me3N/H2O/Solvent Medium[J].Chinese Chemical Letters,2005,16(11):1427-1430. |
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| Authors: | Ke;HE;Zheng;Hong;ZHOU;Hong;Ying;TANG;Guo;Feng;ZHAO;Chu;Chi;TANG |
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| Abstract: | |
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| Keywords: | Chiral activated alkene asymmetric Baylis-Hillman reaction aromatic aldehyde diastereoselectivity |
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