Toward the synthesis of cobyric acid. Enantioselective syntheses of completely differentiated ring D synthons |
| |
| Authors: | Wang Hui Tassa Carlos Jacobi Peter A |
| |
| Affiliation: | Department of Chemistry, Dartmouth College, Hanover, New Hampshire 03755, USA. |
| |
| Abstract: | Alkyne acids 11 were prepared in an enantioselective fashion from allylic ester derivatives 18 or 20 by Ireland-Claisen rearrangement, followed by Si-assisted elimination of HBr. The title compounds are attractive ring D synthons for an ongoing synthesis of cobyric acid. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
