Development and application of nano-flavor-drug carriers in neurodegenerative diseases |
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| Authors: | Wei-Hong Ji Zuo-Bing Xiao Gui-Ying Liu Xin Zhang |
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| Affiliation: | a State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China;b School of Perfume and Aroma Technology, Shanghai Institute of Technology, Shanghai 200233, China;c Shanghai Research Institute of Fragrance & Flavor Industry, Shanghai 200232, China;d Department of Pediatrics, Capital Medical University Affiliated Beijing Anzhen Hospital, Beijing 100029, China |
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| Abstract: | Neurodegenerative disease is one of the serious diseases of the human nervous system. There is no effective way to treat neurodegenerative diseases. Flavors such as curcumin, coumarin, have attracted increasing attention due to having a beneficial therapeutic effect on Alzheimer's disease and Parkinson's disease. But the use of most drugs is limited in clinical treatment because of blood-brain barrier. The use of nano-drug carriers such as liposomes, polymer micelles, polymer nanoparticles and magnetic nanoparticles, which can carry drugs across the blood-brain barrier, has brought hope for the treatment of neurodegenerative diseases. |
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| Keywords: | Neurodegenerative diseases Flavors Nano-drug carriers |
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