Rapid and mild synthesis of quinazolinones and chromeno[d]pyrimidinones using nanocrystalline copper(I) iodide under solvent-free conditions |
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Authors: | Shahrzad Abdolmohammadi Samira Karimpour |
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Affiliation: | Department of Chemistry, Faculty of Science, East Tehran Branch, Islamic Azad University, PO Box 33955-163 Tehran, Iran |
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Abstract: | This paper describes a very simple, efficient synthesis of quinazolinones and chromeno[d]pyrimidinones from the reaction of aryl aldehydes, urea/thiourea and active methylene compounds(dimedone/4-hydroxycoumarin) using nano-sized CuI particles under solvent-free conditions. The highlights of this new method are based on using an effective and recyclable catalyst, affording high yields of products, mild reaction conditions, facile work-up and purification. |
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Keywords: | Chromeno[d]pyrimidinones Copper(I) iodide nanoparticles Quinazolinones Solvent-free conditions |
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