Clean synthesis of novel spiro[indene-2, 2'-[1, 3, 5]-oxathiazine]-1, 3-diones in water |
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| Authors: | Mahboobeh Salehpour Javad Azizian Hassan Kefayati |
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| Institution: | a Department of Chemistry, Science and Research Branch, Islamic Azad University, P. O. Box 19395-1775, Tehran, Iran;
b Department of Chemistry, Rasht Branch, Islamic Azad University, Rasht, Iran |
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| Abstract: | In this work, we have designed an efficient and convenient method for the synthesis of novel spiroindene-2,2'-1,3,5]oxathiazine]-1,3-diones by the one-pot, three component condensation of tetramethyl guanidine, ninhydrin, and isothiocyanates in water. Easy purification, green reaction conditions, easy performance and good yields are some advantages of this procedure. |
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| Keywords: | Spiro[indene-oxathiazine] Tetramethyl guanidine Ninhydrin Oxathiazine |
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