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A facile synthesis of novel unsymmetrical N-(4-oxo-2-phenyl-3(4H)-quinazolinoyl)-N-(aryl)acetamidines |
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| Authors: | Rasool Khan Mohammad Arfan |
| Institution: | a Department of Chemistry, Abdul Wali Khan University, Mardan-23200, NWFP, Pakistan;b Institute of Chemical Sciences, University of Peshawar, Peshawar-25120, Pakistan;c University of Saskatchewan, Department of Chemistry, Saskatoon S7N 5C9, Canada;d HEJRIC, International Center for Chemical and Biological Sciences, University of Karachi, Karachi-75270, Pakistan |
| Abstract: | A series of novel unsymmetrical N-(4-oxo-2-phenyl-3(4H)-quinazolinoyl)-N-(aryl)acetamidines was synthesized by reacting ethyl(1E)-N-(4-oxo-2-phenylquinazolin-3(4H)-yl)ethanimidoate (2) and suitable reactive aromatic amines. Structures determination of the synthesized compounds was carried out using spectroscopic techniques including; IR, 1H-NMR, and mass spectrometry. Structural effects on reactivity were also studied. |
| Keywords: | 3-Amino-2-phenyl-4(3H)-quinazolinone Triethylorthoacetate Unsymmetrical N-(4-oxo-2-phenyl-3(4H)-quinazolinoyl)-N-(aryl) acetamidines |
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