New triterpenoids isolated from the root bark of Ulmus pumila L |
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Authors: | Wang Dong Xia Mingyu Cui Zheng |
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Institution: | Department of Pharmacognosy, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University. |
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Abstract: | Three new triterpenoids, 1-3, were isolated from the dried root bark of Ulmus pumila. Along with the three new compounds, six known triterpenoids, epifriedelanol (4), friedelin (5), oleanolic acid (6), maslinic acid (7), camaldulenic acid (8), and arjunolic acid (9) were also isolated. The structures of new compounds were established as ulmudiol (bauer-7-ene-1alpha,3beta-diol, 1), dehydroulmudiol bauer-7,9(11)-diene-1alpha,3beta-diol, 2], and ulmuestone 3alpha-hydroxy-11alpha-(4'-hydroxy-3'-methoxy)benzoyloxybauer-1-one, 3], on the basis of extensive 1D and 2D NMR spectroscopic data interpretation. In addition, the cytotoxic activities of these compounds are also reported. |
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