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Effect of ethanolic extract of Rubia peregrina L. (Rubiaceae) on monoamine-mediated behaviour
Authors:Kasture Sanjay  Pawar Anupama  Kasture Ameya  Foddis Caterina  Frau Maria Assunta  Maxia Andrea
Institution:Department of Pharmacology, MGV's Pharmacy College, Panchavati, Nashik 422003, India.
Abstract:In the traditional system of medicine in Sardinia, Rubia peregrina (RP) is reported as an aphrodisiac herb. Since aphrodisiacs may also have dopaminergic activity, and there can be a reciprocal relationship between dopaminergic and serotonergic functions in the central nervous system, the aim here was to study the effect of the ethanolic extract of the aerial parts of R. peregrina on monoamine-mediated behaviour. The RP (100 and 200?mg?kg(-1) intraperitoneally) significantly inhibited haloperidol (1?mg?kg(-1) i.p.) induced catalepsy in mice (p?
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