One-dimensional reaction coordinates for diffusive activated rate processes in many dimensions |
| |
Authors: | Berezhkovskii Alexander Szabo Attila |
| |
Institution: | Mathematical and Statistical Computing Laboratory, Division for Computational Bioscience, Center for Information Technology, National Institutes of Health, Bethesda, MD 20892, USA. |
| |
Abstract: | For multidimensional activated rate processes controlled by diffusive crossing of a saddle point region, we show that a one-dimensional reaction coordinate can be constructed even when the diffusion anisotropy is arbitrary. The rate constant, found using the potential of mean force along this coordinate, is identical to that predicted by the multidimensional Kramers-Langer theory. This reaction coordinate minimizes the one-dimensional rate constant obtained using a trial reaction coordinate and is orthogonal to the stochastic separatrix, the transition state that separates reactants from products. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|