Anti-neuraminidase activity of chemical constituents of Balanophora involucrata

Balanophora involucrata J. D. Hooker has been known to possess potential anti-inflammatory and antibacterial activities; however, its antiviral activity has not been evaluated so far. In order to find new neuraminidase inhibitors (NAIs), the neuraminidase (NA) inhibition activity of different B. involucrata extracts was evaluated. In this study, an in vitro NA inhibition assay was performed to identify which extract of B. involucrata exhibits (maximal) inhibitory activity against NA. Ultra high performance liquid chromatography/quadrupole time-of-flight–tandem mass spectroscopy (MS/MS) and molecular docking techniques were used to identify the specific compounds responsible for the anti-influenza activity of the extract, and to explore the potential natural NAIs. The ethyl acetate extract of B. involucrata exhibited significant inhibitory activity against NA with 50% inhibitory concentration (IC₅₀) value of 159.5 μg/mL. Twenty compounds were identified according to the MS/MS spectra; among them two compounds (quercitrin and phloridzin) showed obvious inhibitory activity against NA, with IC₅₀ of 311.76 and 347.32 μmol/L, respectively. This study suggested that B. involucrata can be a potential natural source of NAIs and may be useful in the fight against ferocious influenza viruses.     

放顶煤工作面综合防灭火技术研究与应用

对江苏大屯煤电公司龙东矿放顶煤工作面的防灭火实用技术进行了阐述。重点分析了放顶煤开采在掘进、回采、停采时期的煤炭自然发火的原因和所采取的针对性防治技术。     

篮球运动中学生损伤病因与预防

通过对体育院系学生问卷调查，了解学生在篮球运动中发生运动损伤病因，提出预防措施。     

洼里煤矿综合防治水技术研究

龙矿集团洼里煤矿在生产过程中，针对主要含水层的不同赋存条件，有的放矢采取不同的防治措施。取得了显著的技术效果，保证了矿井的安全生产，对同类型煤矿防治水工作具有借鉴作用。     

谈家庭害虫的危害及防治

家庭是人们生活居住的重要场所，伴人而居的害虫影响到人们的生活质量。因此，采用环境卫生防治、保管技术防治、化学防治、物理与机械防治、人工捕杀害虫等措施，能够有效地改善家庭生活环境。     

邓小平对外开放有关论述与经济全球化问题探索

邓小平关于对外开放的理论 ,不仅明确了中国参与经济全球化的必然性 ,同时也指出了中国在经济全球化进程中所面临的挑战和应对的措施 ,使我们能够积极面对经济全球化的客观趋势 ,采取有力的措施 ,扬长避短 ,抓住机遇 ,迎接挑战 ,变不利为有利 ,在经济全球化竞争中立于不败之地     

SARS研究进展

本文对SARS病原学、流行病学、预防和治疗的研究进展进行了综述。     

关于武昌鱼败血症的防治

论述武昌鱼败血症的病原体 ,发病的主要症状 ,流行情况 ,病原体致病条件及防治的主要措施。     

Erosion and Sediment Production in Small Watershed in Purple Hilly Areas and Prevention Techniques

Purple Soil distributes extensively and mainly in China. Because of abundant easily weatherable parent rocks/materials and unstable soil structure, and also influenced by parent materials, usage systems, and slope gradients, erosion and sediment production of purple soils are very severe with main fashions of water erosion and gravitational erosion. Basing on observed data in small watersheds, rainfall erosivity,vegetation coverage, previous soil water content, flow and relating factors such as climate, topograph of small watershed,land usage, and soil kinds are all the influence factors of erosion and erodibility of purple soil as well as sediment production and transport in small watershed of purple hilly areas.The effective technological countermeasures of ecosystem restoration, agricultural tillage for water conservation and erosion prevention, agriculture project, and soil changing for fertility and anti-erosion were provided.     

刮板输送机断链事故的原因及预防

刮板输送机是煤矿生产的重要运输设备，对于整个工作面的安全起着至关重要的作用。分析了造成刮板输送机断链事故的主要原因，并有针对性地提出了预防措施。