Synthetic study of (+)-anthramycin using ring-closing enyne metathesis and cross-metathesis

Synthesis of (+)-anthramycin was examined. A pyrrolobenzodiazepine skeleton could be synthesized by reductive cyclization of pyrrolidine derivative, which was obtained by enyne metathesis. The conjugated enamide ester part of (+)-anthramycin derivative was constructed by cross-metathesis.     

带利息力和干扰的批量索赔一般到达风险模型

本文在经典风险模型的基础上,将索赔到达过程推广为更新过程,索赔可以批量到达,且带有常数利息力和Brown运动干扰项,得到一个新的风险模型,运用Markov骨架过程的方法,得出盈余过程的瞬时分布和生存概率.     

GI／G／1单重休假随机服务系统的马氏骨架方法

文献[1]引入一类具有广泛应用前景的随机过程-Markov骨架过程。借助Markov骨架过程的方法研究GI/G/1单重休假服务系统队长，及t时刻到达顾客等待时间的瞬时概率分布。     

Neosappanone A, a xanthine oxidase (XO) inhibitory dimeric methanodibenzoxocinone with a new carbon skeleton from Caesalpinia sappan

A novel dimeric methanodibenzoxocinone, named neosappanone A (1), possessing a unique unprecedented novel carbon framework, has been isolated from the heartwood of Caesalpinia sappan L. of Vietnam, and its structure was elucidated on the basis of spectroscopic analysis. Neosappanone A (1) competitively inhibited xanthine oxidase in a concentration-dependent manner (IC₅₀, 29.7 μM; K_i, 16.3 μM).     

中国近海儒艮骨骼的研究

根据捕自广西北海市近海的５头儒艮（３雌２雄）标本详细描述。中国近海产的儒艮体长２２１ｃｍ～２９３ｃｍ,最大体重４５５ｋｇ。椎式为Ｃ７＋Ｔ１８－１９＋Ｌ５＋Ｃａ２５－２９＝５５－６０。指式（不包括掌骨）为Ⅰ１,Ⅱ３,Ⅲ３,Ⅳ３,Ⅴ２。     

Domino allylation and cyclization of ortho-alkynylbenzaldehydes with allyltrimethylsilane catalyzed by Pd(II)-Cu(II) bimetallic systems

The reaction of ortho-alkynylated benzaldehydes 1 with allyltrimethylsilane under the Pd(OAc)₂-CuCl₂ catalyst system gave the isochromene derivatives 2 together with the chlorinated products 3. When the reaction was conducted in the presence of half equiv of H₂O, the formation of 3 was suppressed and 2 was obtained in good to high yields. When the reaction of 1a was carried out with trimethylsilylcyanide instead of allylsilane, the cyano group-substituted isochromene 9 was obtained in 94% yield.     

基于势能平衡的图像骨架抽取算法

基于骨架的基本特征和势能的概念，提出了一种基于势能平衡方式的二值图像骨架抽取算法．将抽取对象的边缘点作为零势能的等势点，计算出处于势能平衡点上的基本骨架点，并据此通过向势能小处延伸的方式构建出骨架，还解决了由于各点周围参考零势能点数量不同而带来的各点势能值间难以比较的问题。通过计算机模拟显示，本算法对于边界噪声影响不太敏感，且在端点处的畸变比最大圆盘方式小。     

骨架密实型降噪路面的试验研究及应用

借鉴沥青玛蹄脂碎石(SMA)路面的配比组成特色,在集料中掺加一定剂量的废旧轮胎橡胶颗粒,以增加沥青混合料的弹性和阻尼性能,使得铺筑的路面(称为骨架密实型降噪路面)具有减小轮胎/路面泵气噪声和阻尼减振降噪的双重效果.室内试验表明,废橡胶颗粒的掺量为集料质量数的1%~3%时,沥青混合料的高温稳定性和低温抗裂性能均得到改善,水稳定性略有下降.试验路的测试结果证明,对小汽车而言,车速在40~80 km.h-1时,与普通沥青混凝土(AC)路面相比,骨架密实型降噪路面可降低噪声2~3 dB(A).     

Stochastic integration,trace and the skeleton of wiener functionals

It is shown that the notion of trace induced by a given complete orthonormal system relates the Skorohod integral with a corresponding Ogawa‐type integral evaluated with respect to the same orthonormal systems. Similarly the multiple Wiener‐Ito integral is shown to be related to a multiple Ogawa‐type integral induced by a complete orthonormal system via the Hu‐Meyer formula with suitably defined multiple traces. The notion of skeleton of a Wiener functional relative to a given orthonormal system is defined and yields what seems to be a “natural” extension of Wiener functionals to the Cameron Martin space and the Wiener processes with a different scale.