Validated Stability-Indicating GC-MS Method for Characterization of Forced Degradation Products of Trans-Caffeic Acid and Trans-Ferulic Acid

When dealing with simple phenols such as caffeic acid (CA) and ferulic acid (FA), found in a variety of plants, it is very important to have control over the most important factors that accelerate their degradation reactions. This is the first report in which the stabilities of these two compounds have been systematically tested by exposure to various different factors. Forced degradation studies were performed on pure standards (trans-CA and trans-FA), dissolved in different solvents and exposed to different oxidative, photolytic and thermal stress conditions. Additionally, a rapid, sensitive, and selective stability-indicating gas chromatographic-mass spectrometric method was developed and validated for determination of trans-CA and trans-FA in the presence of their degradation products. Cis-CA and cis-FA were confirmed as the only degradation products in all the experiments performed. All the compounds were perfectly separated by gas chromatography (GC) and identified using mass spectrometry (MS), a method that additionally elucidated their structures. In general, more protic solvents, higher temperatures, UV radiation and longer storage times led to more significant degradation (isomerization) of both trans-isomers. The most progressive isomerization of both compounds (up to 43%) was observed when the polar solutions were exposed to daylight at room temperature for 1 month. The method was validated for linearity, precision as repeatability, limit of detection (LOD) and limit of quantitation (LOQ). The method was confirmed as linear over tested concentration ranges from 1−100 mg L⁻¹ (r²s were above 0.999). The LOD and LOQ for trans-FA were 0.15 mg L⁻¹ and 0.50 mg L⁻¹, respectively. The LOD and LOQ for trans-CA were 0.23 mg L⁻¹ and 0.77 mg L⁻¹, respectively.     

正交各向异性矩形板受迫振动的三维分析

从正交各向异性三维弹性动力学的控制方程出发，在求得四边简支矩形板自由振动频率和位移振型的基础上，构造了受迫振动的位移函数；利用自由振动位移振型的正交性，将控制方程的空间变量和时间变量分离，得到了广义质量、广义力和频率表示的关于时间的2阶常微分方程，从而得到了正交各向异性弹性矩形板在受迫振动下的位移场和应力场．给出了本文方法与薄板理论的算例．     

小型建筑施工企业机械设备维修保养制度探析

小型建筑施工企业建立科学合理的机械设备维修保养制度，是保证工程质量和提高企业经济效益的重要环节。     

高阶非线性时滞差分方程解的渐近性

研究如下的具强迫项的高阶非线性时滞差分方程△^my(n) u(n)l↑∑i=1 gi(y(n-τ))=v(n)其中，m≥1，u,v：N→R，gi：R→R且τ∈{0，1，2，3，…)，i=1，2，…，l，得到了使该方程的解具有某种渐近性态的充分条件。     

用电磁打点计时器进行受迫振动实验--介绍我校的一个自学物理实验

介绍一种用简单的方法进行的受迫振动实验。     

带强迫项变系数组合KdV方程的显式精确解

通过构造两个新的Riccati方程组，推广了Riccati方法，使其具有简洁的形式，丰富和发展了已有的结果，借助Mathematica软件，求出了带强迫项变系数组合KdV方程的一些精确解，包括各种类孤波解、类周期解和变速孤波解. 关键词： Riccati方程组 变系数组合KdV方程 强迫项 类孤波解     

不良导体导热系数测定实验中仪表风扇对实验结果的影响

根据对物体冷却规律的分析,并从实验结果比较,指出稳态法测不良导体导热系数实验中,设置散热盘的冷却过程应与其在稳态过程时的强迫对流散热方式保持一致.     

受迫振动演示实验装置

本文叙述用示波器显示来演示受迫振动的实验装置，可直观地向学生展示受迫振动的幅频特性和相频特性。     

The Development of Gas-flow Modulation for High-frequency MTDSC measurements

The purpose of this study was to investigate the feasibility of modulating the temperature programme of a conventional DSC by use of an alternating gas-flow system. Modulated temperature differential scanning calorimetry (MTDSC) is an important thermal analysis technique but suffers from a limited applicable frequency range due to the mass of the sample and DSC cell leading to the impingement of thermal conductivity effects. We suggest that the frequency limit can be increased by replacing the cell as the source of temperature modulation with an external gaseous source, directed towards the sample and reference pans. In this evaluation, an alternating gas-flow was passed through a line to a forced gas-flow accessory (FGFA). The FGFA consisted of two matched cylinders containing chambers that allowed pre-temperature-equilibration of the stream of gas before it was passed over the sample and reference pans. The development of this device revealed the essential practical requirements of gas-flow modulation for high-frequency temperature modulation. These include the following: an appropriately sealed tunable gas supply to both sample and reference pans, an effective method for high-frequency cycling of the gas-flow rate, a small aperture to deliver the flowing gas directly over the pan and a temperature equilibration chamber. The results from samples of quenched PET and amorphous Saquinavir indicate that gas-flow modulation is indeed feasible, with the FGFA able to raise the attainable temperature modulation frequency by an order of magnitude compared to conventional MTDSC. This revised version was published online in August 2006 with corrections to the Cover Date.