A New Local Search Algorithm for the Job Shop Scheduling Problem

0　IntroductionThejobshopschedulingproblemwithwhichwearecon cernedconsistsinschedulingasetofjobsonasetofma chinesfortheobjectiveofminimizingthemake span ,i.e .themaximumoftimeneededforfinishingalljobs,whichissubjecttotheconstrainsthateachjobhasafixedprocessingorderthroughthemachinesandeachmachinecanprocessatmostonejobatatime .ThisproblemisNP hardandevenisoneofthehardestcom binationaloptimizationproblems.Itiswellknownthatonlysmallsizeprobleminstancescanbesolvedwithinareasonablecomputa tionalti…     

时代、民族、个性与绘画的反思

论述了时代、民族、个性之间相辅相成的关系,举出了不同国度、不同历史时代、不同学术流派的具体事例,阐述了在绘画创作中民族传统是土壤、时代是空气、艺术家的个性是推动力的观点,及如何处理三者间的关系,提出艺术家个性化的误区及对策.     

The enormity of the zinc deficiency problem and available solutions; an overview

The societal cost of micronutrient deficiency (MND) or the “hidden hunger” is in millions of dollars/year, reducing the GDP of some countries by as much as 11%. Zn is an important micronutrient for both plants and animals. An estimated 17% of the world population, or around 1.1 billion people, are at the risk of zinc (Zn) deficiency. The deficiency has been related to adverse pregnancy outcomes, stunted growth, premature deaths, immune system dysfunctions, neuro-behavioral disorders, and recently with the failure to recover from COVID-19. These health risks associated with Zn deficiency have compelled FAO and WHO to recommend Zn fortification of diet. Correcting Zn deficiency is a challenge due to several reasons. Close to half of the agricultural soils are Zn deficient, and chemical Zn fertilizers are costly and ineffective. Developing Zn-rich crops through plant breeding and genetic engineering is challenging. Zn-dense diet is costly and cannot be implemented in the low-income region most affected by Zn deficiency. Lack of consensus among regulatory bodies on defining and diagnosing Zn deficiency in plants and Humans. Awareness and other sociocultural issues. Among the most important available solutions are zinc biofortification of the cereal crops, use of zinc biofertilizers, development of Zn-efficient crops with reduced phytate content. The use of Zn supplements, dietary modification, and diversification, especially with fish, are proposed as the most accessible and affordable solutions. Awareness programs in areas suffering the most from Zn deficiency are required. Despite the suggestions from FAO and WHO, global efforts to combat Zn deficiency matching those for combating diseases like HIV are not in place. Coordinated efforts of the international community, especially policy-makers, agricultural scientists, dieticians, physicians, and others, are required to address the issue of hidden hunger.     

Late-Stage Diversification of Tryptophan-Derived Biomolecules

Pd-mediated reactions have emerged as a powerful tool for the site-selective and bioorthogonal late-stage diversification of amino acids, peptides and related compounds. Indole moieties of tryptophan derivatives are susceptible to C²H-activation, whereas halogenated aromatic amino acids such as halophenylalanines or halotryptophans provide a broad spectrum of different functionalisations. The compatibility of transition-metal-catalysed cross-couplings with functional groups in peptides, other biologically active compounds and even proteins has been demonstrated. This Review primarily compiles the application of different cross-coupling reactions to modify halotryptophans, halotryptophan containing peptides or halogenated, biologically active compounds derived from tryptophan. Modern approaches use regio- and stereoselective biocatalytic strategies to generate halotryptophans and derivatives on a preparative scale. The combination of bio- and chemocatalysis in cascade reactions is given by the biocompatibility and bioorthogonality of Pd-mediated reactions.     

关于构建和谐社会若干问题的思考

构建社会主义和谐社会是新一届领导集体提出的重要战略思想,这具有重要的理论意义和实践价值。本文采用社会学方法,对构建和谐社会应注意的五个基本问题展开论证。对构建社会主义和谐社会提出了自己的一些看法。     

论批判思维视角下的多元化全运会

全运会总会留给我们许多思考的问题，回顾近几届全运会，赛场内外的怪现象层出不穷。有禁药丑闻的污秽，有消极比赛的哗然，有不合理制度的黑暗，一时间使全运会成了丑闻频发的舞台。从多个视角去审视全运会中的种种现象，研究表明：从体育大国迈向体育强国，中国体育正在经历转型期，全运会与群众体育的协调关系依然有待改进，竞技体育对群众体育的带动依然亟待加强。全运会该如何回到全民体育的轨道，这样的体育强国才是我们所期待的。     

构建多元与互动的电子阅览室探讨

以四川理工学院图书馆电子阅览室为例,从实体设施、数字资源、互动活动3个方面,探讨了如何构建多元、数字、互动的电子阅览室,并通过实践证明了电子阅览室能够为读者提供"一次满足"的服务。     

小学低年级语文识字教学浅议

语文是一门基础学科,而识字教学是基础中的基础.因此,在识字教学中,我们应培养孩子的识字能力,更应该培养孩子的识字兴趣,教给孩子识字方法,使我们的识字教学取得事半功倍的效率.     

On the Development of Titanium κ1-Amidinate Complexes,Commercialized as Keltan ACE™ Technology,Enabling the Production of an Unprecedented Large Variety of EPDM Polymer Structures

ARLANXEO Elastomers has developed and commercialized Keltan ACE™ technology, a class of half-sandwich cyclopentadienyl κ¹-amidinate metal complexes, which are extremely active for the production of first-class ethylene/propylene/diene copolymers (EPDM). In this review, the development and some of the key features of the Keltan ACE™ catalyst system are presented. Many different ACE catalysts have been synthesized over the past years, including bridged and bimetallic catalysts. With Keltan ACE™, a complete range of EPDM products with similar polymer characteristics as their Ziegler–Natta (ZN) counterparts can be produced, including variations containing very high 5-ethylidene-2-norbornene (ENB) contents, controlled long chain branching, very high molecular weight, as well as oil-extended products. Moreover, other EPDM structures can be polymerized. The Keltan ACE™ catalyst technology also allows the production of EPDMs with very high amounts of dicyclopentadiene (DCPD) or 5-vinyl 2-norbornene (VNB) without excessive gelation and reactor fouling, that is, products that cannot or are extremely difficult to obtain via classical ZN catalysis. In a next step, high-VNB-EPDM can be postreactor modified, for example, via metathesis chemistry. In addition, EPDM polymers with a very broad or even bimodal molecular weight distribution can be obtained in a single reactor with certain ACE catalyst structures at particular activator/precatalyst ratios. © 2017 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2017 , 55, 2877–2891     

高师应用数学专业多元化人才培养的探索与实践

阐述了高师应用数学专业"平台"+"模块"的多元化人才培养的探索与实践,提出了以学生为本,职业规划引导,延伸专业课堂,共享教育资源,构建互助平台,获取资格认证的"目标引导"式培养模式,指出了需要进一步解决的问题和建议.