Chemical Profiles and Pharmacological Properties with in Silico Studies on Elatostema papillosum Wedd

The current study attempted, for the first time, to qualitatively and quantitatively determine the phytochemical components of Elatostema papillosum methanol extract and their biological activities. The present study represents an effort to correlate our previously reported biological activities with a computational study, including molecular docking, and ADME/T (absorption, distribution, metabolism, and excretion/toxicity) analyses, to identify the phytochemicals that are potentially responsible for the antioxidant, antidepressant, anxiolytic, analgesic, and anti-inflammatory activities of this plant. In the gas chromatography-mass spectroscopy analysis, a total of 24 compounds were identified, seven of which were documented as being bioactive based on their binding affinities. These seven were subjected to molecular docking studies that were correlated with the pharmacological outcomes. Additionally, the ADME/T properties of these compounds were evaluated to determine their drug-like properties and toxicity levels. The seven selected, isolated compounds displayed favorable binding affinities to potassium channels, human serotonin receptor, cyclooxygenase-1 (COX-1), COX-2, nuclear factor (NF)-κB, and human peroxiredoxin 5 receptor proteins. Phytol acetate, and terpene compounds identified in E. papillosum displayed strong predictive binding affinities towards the human serotonin receptor. Furthermore, 3-trifluoroacetoxypentadecane showed a significant binding affinity for the KcsA potassium channel. Eicosanal showed the highest predicted binding affinity towards the human peroxiredoxin 5 receptor. All of these findings support the observed in vivo antidepressant and anxiolytic effects and the in vitro antioxidant effects observed for this extract. The identified compounds from E. papillosum showed the lowest binding affinities towards COX-1, COX-2, and NF-κB receptors, which indicated the inconsequential impacts of this extract against the activities of these three proteins. Overall, E. papillosum appears to be bioactive and could represent a potential source for the development of alternative medicines; however, further analytical experiments remain necessary.     

论峡江地区“烧龙”与“烧畬”的区别和联系

唐宋时期峡江地区“击鼓焚山”的民俗活动是远古时代尚巫之风的残存,其目的是为烧龙祈雨以禳除旱灾;而“烧畬下种”则是自远古“刀耕火种”传承下来的一门农耕技术,但由于“占卜伺雨”的仪式亦使它带上了一些巫风色彩。二者既有明显的区别又有一定的联系。     

鲁西北蜜源植物资源调查

首次报导了鲁西北蜜源植物的种类和花期，对充分利用蜜源资源，合理安排养蜂生产具有重要的指导意义．经充分调查并根据孢粉学知识，分析总结出鲁西北共有主要蜜源植物１５种，辅助蜜源植物１０４种，共计１１９种．     

炼钢─连铸─热轧直接热装一体化计划

从计划角度重点分析了钢铁生产中炼钢、连铸、热轧三者之间联接的较高模式－直接热装轧制计划系统的实现方式，并给出了较为具体的方案。     

我国北宋时期占城稻的推广与发展

占城稻原产于古占城国(今越南中南部)。关于北宋时期占城稻引种时间、推广与发展的成果和意义，因史料不详，众说纷纭。结合当时自然、社会条件，通过分析资料，认为在北宋时期，因人口增加，粮食短缺，政府大力倡导、认真组织，民间积极响应的社会条件下，利用占城稻的耐旱特性，扩大粮食种植面积，达到了增加粮食产量的目的，并为以后江南地区稻麦两熟制的发展莫定了基础。     

根癌农杆菌介导AtNHX1基因转化小麦

利用根癌农杆菌对 3种基因型小麦进行了转化研究 .发现基因型对转化有明显影响 .将小麦品种烟优 36 1、烟 10 3、核生 3号的胚性愈伤组织用含报告基因NPTⅡ和抗盐基因Na H 反向转运AtNHX1的农杆菌菌株pROK2AT GV310 1感染和共培养后 ,用巴龙霉素 5 0 - 15 0mg L筛选抗性愈伤组织及转化植株 .对抗性植株的总DNA用AtNHX1基因的特异引物进行PCR检测 ,目的基因的PCR阳性频率为 1.3(烟 10 3)和 2 .9% (核生 3号 ) .Southern杂交证实外源基因已经整合到小麦的基因组中     

发电厂电气部分课程的工学一体化教学改革探索与实践

详细论述了近年来我们对《发电厂电气部分》课程所做的一系列教学改革与探索，提出了工学一体化教学改革模式，该模式旨在将工程实际贯穿于整个教学活动中，将工程思想、理论学习和工程训练相互融通，使其成为一个动态的整体，采用该模式教学，能够强化学生动手能力和培养创新思维，建立工程思想．     

长春市园林木本地被植物的应用与发展

通过对长春市园林木本地被植物应用的调查研究表明，目前长春市园林绿化常见木本地被植物共有21种：其中，木质藤本地被植物有4种，隶属2科，3属；矮灌木地被植物有10种，隶属5科7属；整形木本地被植物有7种，隶属4科6属。本文介绍了木本地被植物的园林应用及生态型，并提出发展长春市园林地被植物的建议。     

Pressurized hot water extraction of berberine, baicalein and glycyrrhizin in medicinal plants

Pressurized hot water extraction (PHWE) using a laboratory made system was applied for the extraction of thermally labile and reasonably polar components such as berberine in coptidis rhizoma, glycyrrhizin in radix glycyrrhizae/liquorice and baicalein in scutellariae radix. PHWE was carried out dynamically at a flow of 1 ml/min, temperature between 95 and 140 °C, an applied pressure of 10-20 bar and extraction time of 40 min. Extraction by PHWE was found to give efficiencies comparable to Soxhlet extraction for baicalein in scutellariae radix and sonication for berberine in coptidis rhizoma, and glycyrrhizin in radix glycyrrhizae. Effects of ethanol added into the water used in PHWE were explored. Pressurized liquid extraction (PLE) with methanol as solvent was used for extraction of baicalein in scutellariae radix. The marker compounds present in the various medicinal plant extracts were determined by gradient elution HPLC.