6σ管理中需要澄清的几个问题

6σ管理作为组织实施连续质量改进的一种经营策略,已引起企业界和学术界的极大兴趣,并在一些企业中得到很好应用。正确实施6σ,需要对其基本概念、假设条件、相关约束等有一个较为全面的了解和认识。本文探讨了6σ文献和应用过程中需要关注的几个问题,其中包括6σ的基本概念和特点;分布假设;过程均值1.5σ漂移的可行性;过程能力指数;短期波动和长期波动;6σ改进和6σ设计等。     

predForm-Site: Formylation site prediction by incorporating multiple features and resolving data imbalance

Formylation is one of the newly discovered post-translational modifications in lysine residue which is responsible for different kinds of diseases. In this work, a novel predictor, named predForm-Site, has been developed to predict formylation sites with higher accuracy. We have integrated multiple sequence features for developing a more informative representation of formylation sites. Moreover, decision function of the underlying classifier have been optimized on skewed formylation dataset during prediction model training for prediction quality improvement. On the dataset used by LFPred and Formator predictor, predForm-Site achieved 99.5% sensitivity, 99.8% specificity and 99.8% overall accuracy with AUC of 0.999 in the jackknife test. In the independent test, it has also achieved more than 97% sensitivity and 99% specificity. Similarly, in benchmarking with recent method CKSAAP_FormSite, the proposed predictor significantly outperformed in all the measures, particularly sensitivity by around 20%, specificity by nearly 30% and overall accuracy by more than 22%. These experimental results show that the proposed predForm-Site can be used as a complementary tool for the fast exploration of formylation sites. For convenience of the scientific community, predForm-Site has been deployed as an online tool, accessible at http://103.99.176.239:8080/predForm-Site.     

沪市新股发行走价方法探析

在对股票价格与每股净资产、每股收益、行业因素、沪市综合指数关系分析的基础上，以2001年3月1日沪市A股开盘价为准对股价与相关指标进行回归，得到新股上市价格的预测模型。然后，根据新股发行后每股净资产随发行价格的提高而增长这一特点进行求解，求出了全面反映每股净资产、每股收益、行业因素、沪市A股综合指数纳新股上市定价模型，该模型共考虑了5种因素，弥补了新股定价只考虑市盈率单一因素的不足。     

江西出口贸易发展中的主要问题及对策

江西省近年来外贸发展迅速,然而,外贸数量型的增长难以掩盖其外贸发展中的问题。本文从分析江西出口贸易发展的现状分析入手,就如何提升江西外贸出口的竞争力谈了自己的看法。     

高校图书馆美术资源数据库建设初探

高校图书馆应该发挥其数字图书馆领域的技术优势,与美术作品的馆藏单位合作,共同建设美术资源数据库。从美术资源的收集和甄别、信息采集、元数据标准、版权问题等方面,探讨了高校图书馆美术资源数据库建设中应注意的问题。     

改革开放前后邓小平知识分子思想探微

援用文献法和比较法,对邓小平知识分子思想的形成、发展及其基本内容进行了阐述,对改革开放前后邓小平知识分子思想做了比较,并分析了改革开放后邓小平特别关心人才问题的原因。在学习贯彻十七大精神的今天,学习和研究邓小平关于知识分子问题的理论和实践,具有重要的现实意义。     

精细化管理模式下期刊现刊工作守则的制定

以精细化管理为指导,介绍了精细化管理下制定工作守则应该遵守的原则及次序,阐述了精细化管理下期刊及现刊工作守则的制定。     

风险投资制度创新分析——基于“种子期”投资的研究

随着国际竞争的日益激烈,我国提出了建立以企业为主体的技术创新体系,并指出现阶段我国企业进行自主创新具有重要意义。创新活动具有高投入、高风险、高收益的特点,需要大量的资金支持,伴随着高新技术产业的产生而产生的风险投资可以提供这种资金支持。但是目前我国风险投资对企业"种子期"的投入不够,使我国企业自主创新能力不强,随着我国经济的发展,加强"种子期"投资不仅是我国高技术产业发展的要求也是风险投资发展到一定阶段的必然选择。因此现阶段必须从国家和风险投资企业两个层面采取措施以加强"种子期"投资。     

氧化数教学争议的化解

Starting with the definition of oxidation number and the development of its concept, the controversial issues in the teaching of oxidation number were discussed in this paper, and the rule that the positive oxidation number of the element should be less than or equal to the total numbers of valence electrons of the atom was put forward to determine the oxidation number. Additionally, the calculation of oxidation number in the compounds with complex structure and unknown structure has been resolved.     

社会法的生成与体系定位

人类在近三百多年的历史中产生并形成了＂援救类、促进类、维权类＂的社会法;其根据是人群之间帮扶脱困的系统——＂狭义社会＂的形成;社会法是基于对解脱人群在实现基本生存权时遇到困难或困境而提供保障的需要,保障人群之间帮扶脱困的法。