Can TMS and DSS be used as NMR references for cyclodextrin species in aqueous solution?

Tetramethylsilane (TMS) can be included by -cyclodextrin (-CD), and sodium 2,2-dimethylsilapentane-5-sulphonate (DSS) can form inclusion complexes with - and -CD. The NMR chemical shifts are changed considerably as a result of the strong interaction between CD and the guest compound in the inclusion complexes. A downfield shift of as much as 0.63 ppm shift downfield has been observed for the protons of external TMS in CD aqueous solution. In view of this, the question arises of whether TMS and DSS can be used as internal references. DSS in D₂O is suggested as an external reference for aqueous cyclodextrin solution in NMR measurements.     

船舶初步设计阶段智能决策支持系统的应用

提出了用于辅助船舶设计者在获取船型要素信息量有限情况下，进行船型方案优选决策的支持系统理论体系框架和模型。将该系统应用于某实船船型方案优选决策，证明该方法是可行的、可靠的。此外，对未来智能决策支持系统在船舶初步设计中的应用前景进行了展望和预测。     

计算机集成过程系统环境下的决策支持系统

基于炼油生产流程的特点，开发了一种计算机集成过程系统环境下的智能型分布式决策支持系统（ＣＬ－ＩＤＤＳＳ），给出了ＣＬ－ＩＤＤＳＳ的系统总体结构．该系统以面向对象技术开发，功能模块丰富，具有模块化强、易于扩充、易于移植、易于维护、通用性强等特点，可以由此系统抽出一个ＤＳＳ生成器     

组织决策支持系统的基本概念及研究框架

在当前对ＯＤＳＳ的各种不同观点的基础上，首先给出了一个ＯＤＳＳ的定义，然后提出一个ＯＤＳＳ的研究框架，以期在此框架的指导下来探讨当前ＯＤＳＳ的研究现状并指导将来对ＯＤＳＳ的进一步的研究方向．     

数据仓库中数据的粒度划分

数据仓库在决策支持系统(DSS)中起着核心作用,而要创建一个好的数据仓库,构造合适的数据粒度模型是要解决的一个重要问题.通过对数据粒度划分方法的分析,结合实例给出了一个划分粒度级别的新思路,提出了解决不同级别间数据查询效率的基本方法.     

基于ERP的决策支持系统在快速消费品行业中的应用研究

介绍了快速消费品行业信息化的现状,指出ERP对提供支持决策信息能力不足的缺点,进而提出在ERP广泛应用的快速消费品行业里,建立基于ERP系统的综合数据仓库决策支持系统的重要性以及广阔前景。     

The Intelligent Decision Support System Model of SARS

Based on the intelligent decision support system, a new method was presented to defense the catastrophic infectious disease such as SARS, Bird Flu, etc.. By using All Set theory, the decision support system (DSS) model can be built to analyze the noise information and forecast the trend of the catastrophe then to give the method or policy to defend the disease. The model system is composed of four subsystems: the noise analysis subsystem, forecast and simulation subsystem, diagnosis subsystem and second recovery subsystem. They are discussed briefly in this paper. This model can be used not only for SARS but also for other paroxysmal accidences.     

Evaluation of SARs for the prediction of skin irritation/corrosion potential–structural inclusion rules in the BfR decision support system†

The German Federal Institute for Risk Assessment (BfR) has developed a Decision Support System (DSS) to assess certain hazardous properties of pure chemicals, including skin and eye irritation/corrosion. The BfR–DSS is a rule-based system that could be used for the regulatory classification of chemicals in the European Union. The system is based on the combined use of two predictive approaches: exclusion rules based on physicochemical cut-off values to identify chemicals that do not exhibit a certain hazard (e.g., skin irritation/corrosion), and inclusion rules based on structural alerts to identify chemicals that do show a particular toxic potential. The aim of the present study was to evaluate the structural inclusion rules implemented in the BfR–DSS for the prediction of skin irritation and corrosion. The following assessments were performed: (a) a confirmation of the structural rules by rederiving them from the original training set (1358 substances), and (b) an external validation by using a test set of 200 chemicals not used in the derivation of the rules. It was found as a result that the test data set did not match the training set relative to the inclusion of structural alerts associated with skin irritation/corrosion, albeit some skin irritants were in the test set.     

四种黄酮类化合物与牛血清白蛋白相互作用的光谱分析

在人体生理pH条件下,利用紫外吸收光谱和荧光光谱研究了槲皮素(QUE)、大豆甙元(DAI)、4′,7-二甲氧基-3′-异黄酮磺酸钠(DISS)和3′-大豆甙元磺酸钠(DSS)四种黄酮类化合物与牛血清白蛋白(BSA)的相互作用,结合反应机理对其进行了初步探讨;并计算了结合位点数和结合常数.紫外吸收光谱分析结果表明,在pH=7.4条件下,黄酮类化合物中疏水性的苯环与BSA疏水腔中的氨基酸残基发生作用,从而导致药物分子的吸收峰红移,用Scatchard拟合法可求得DAI及DSS与BSA的结合常数.荧光光谱分析结果表明,BSA对DAI、DISS和DSS均有明显的敏化增强效应,计算得到的增强速率常数分别为1.39×1011,7.72×1011和1.93×1012L·s-1·mol-1,并可求得结合位点数和结合常数.     

大气质量评价决策支持系统

以阜新市污水处理厂建设过程对周边大气环境的影响评价为例,采用从定性到定量的综合集成方法和Visualc＋＋编程技术,把决策理论基本知识引入到环境评价工作中,对此交叉领域展开深入研究,建立了大气质量评价决策支持系统（AA-DSS）a研究结果表明,该系统简单、实用且易于维护,大大缩短了大气质量评价工作流程,提高了工效,同时为决策理论在整个环境质量评价中的推广应用奠定了基础。