Synthesis of optically active 6-substituted 2-(aminomethyl)chromans

Three novel, optically active, 6-substituted 2-(aminomethyl)chromans were synthesized from readily available chroman 2-carboxylic acid precursors. These chroman-containing primary amines are useful building blocks for the synthesis of chroman-derived pharmaceutical agents.     

建筑与寻常景观——华南理工大学建筑设计院创作室环境设计

从设计定位、空间布局、技术细节三方面入手,详细介绍了华南理工大学建筑设计院创作室环境设计的理念和手法。论述了作为建筑设计事务所周边环境的设计,如何做到如寻常景观一般与原有环境相融合的协调,并从中总结经验和教训。     

智能CAD／CAM技术对建筑机械业的影响

本文首先介绍ＣＡＤ／ＣＡＭ的产生及发展。然后谈ＣＡＤ／ＣＡＭ对建筑机械业的影响。本主独道见解是：ＣＡＤ／ＣＡＭ技术对建筑机械业影响巨大，一个全新的计算机辅助建筑工程制造ＣＡＥＭ概念将产生。当ＣＡＥＭ实现时，建楼房将象儿童搭积木房子一样轻而易举。“安得广厦万千间，使得天下寒士尽欢颜”梦想会成真。     

Synthetic applications of aryl radical building blocks for cyclisation onto azoles

2-(2-Bromophenyl)ethyl groups have been used as building blocks in radical cyclisation reactions onto azoles to synthesise tri- and tetra-cyclic heterocycles. 2-(2-Bromophenyl)ethyl methanesulfonate was used to alkylate azoles (imidazoles, pyrroles, indoles and pyrazoles) for the synthesis of the radical precursors. Cyclisations of the intermediate aryl radicals yield new 6-membered rings attached to the azoles. The aryl radicals undergo intramolecular homolytic aromatic substitution onto the azole rings. Tributylgermanium hydride has been used with success to replace the toxic and troublesome tributyltin hydride. Initial studies show that the protocol can be used on solid phase resins. The molecular and crystal structures of methyl 5,6-dihydroimidazo[5,1-a]iso-quinoline-1-carboxylate and methyl 5,6-dihydroimidazo[2,1-a]isoquinoline-3-carboxylate were determined by X-ray crystallography.     

化“材”为“筑”

Chemistry is a central, practical and creative discipline. The development of chemistry plays an important role in the progress of science and society, as well as the improvement of the quality of human life. This paper introduces the chemical knowledge of stone, concrete, glass and other inorganic nonmetallic building materials by the anthropomorphically story. Taking nanomaterials as an example, the prospect of building materials development in the future is put forward.     

Detector comparison for sulfur and chlorine detection with laser induced breakdown spectroscopy in the near-infrared-region

Laser-induced breakdown spectroscopy has been employed for the investigation of the sulfur and chlorine content of building materials. Both, chloride and sulfate ions are major damaging species affecting the stability and lifetime of a structure. Chlorine and sulfur are mostly detected in the VUV and the NIR. In case of building materials the main elements like calcium or iron have many strong spectral lines over the whole spectral range, so that trace elements can only be detected in spectral windows unaffected from these lines. With regard to a preferably simply, robust against dust and vibrations and portable setup only the NIR spectral features are used for civil engineering applications.

Most detectors, mainly CCD cameras have rapidly decreasing quantum efficiency in the NIR. Also the quantum efficiency of the photocathode of CCD-Detectors with image intensifier is decreasing in the NIR. Different CCD-detectors were tested with respect to high quantum efficiency and high dynamic range, which is necessary for simultaneous detection of weak spectral lines from trace elements and intense spectral lines from main elements.

The measurements are made on reference samples consisting of cement, hydrated cement, cement mortar and concrete with well-defined amounts of the trace elements. Experimental conditions are chosen for an optimum intensity of the trace element spectral lines. The detector systems are compared by limit of detections and the signal to noise ratio.     

Highly regioselective lipase-catalyzed acetylation and hydrolysis of acyclic α,α′-alkenediols and their diacetates

Highly regioselective transformation of acyclic α,α′-alkenediols and their corresponding diacetates to monoacetates using lipase was accomplished. The acetylation of the α,α′-alkenediol regioselectively gave (E)-monoacetate, whereas the (Z)-monoacetate were obtained by hydrolysis of the α,α′-diacetate.     

建筑材料与装饰材料对室内γ辐射水平的影响

为防护建筑材料和装饰材料的γ辐射对室内环境污染,选择不同建材和不同装饰材料的居室,分别测定室内地板、墙面γ外照射量率和室内γ外照射量率、室内γ辐射吸收剂量率;结果表明在测定的建材γ外照射量率中,红砖和废渣砖所建住宅γ辐射差别无统计学上差异,但两者与青砖比较差异有统计学意义著;装饰材料中花岗岩γ辐射最强,木地板最低.室内γ外照射量率主要来自辐射最强的建材和装饰材料.1997年测定的数据与2005年测量的数据之间差异没有统计学意义,认为建筑时间对不同建材室内γ外照射量率没有影响.     

对培育建筑企业技术创新能力的思考

知识经济时代 ,知识资源已成为企业竞争的核心 ,培育建筑企业技术创新能力 ,丰富建筑企业知识资源 ,是实施建筑企业科技兴业、质量兴业和输出兴业战略的迫切需要 ,通过建筑企业的观念创新、系统规划、管理创新、机制创新、文化创新、优化人才资源、强化教育培训、积极引进先进技术、加大投资力度、全员互动来培育和提高其技术创新能力 ,以促进建筑企业技术进步 ,增强建筑企业的国际竞争能力     

建筑结构设计软件动力时程分析功能比较

利用SATWE、MIDAS/Building和ETABS软件分别对结构地震作用进行计算以获得其在地震作用下的反应,来判断结构整体的安全性和可靠性.对3种软件在前处理、分析过程中、后处理3方面进行对比,得出在前处理中MIDAS/Building在建模、选波和调波方面具有一定的优势,并且在后处理方面提供了丰富的后处理功能,便于操作人员快速查询结果.