碳纳米管被“激光镊子”牵鼻走

~~碳纳米管被“激光镊子”牵鼻走@汪道友~~     

Science Letters： A synthetic Toll-like receptor 2 ligand decreases allergic immune responses in a mouse rhinitis model sensitized to mite allergen

It has been proposed that activation of Toll-like receptors （TLRs） plays crucial roles in the polarization of adaptive immune responses. A synthetic Toll-like receptor 2 （TLR2） ligand, Pam3CSK4, has been reported to modulate the balance of Th1/Th2 responses. We evaluated the modulation effect of Pam3CSK4 on allergic immune response in a mouse rhinitis model sensitized to house dust mite allergen （HDM）. Mice were sensitized and challenged with Dermatophagoidesfarinae allergen （Der f）, and then the allergic mice were treated by Pam3CSK4. Nasal allergic symptoms and eosinophils were scored. Der f-specific cytokine responses were examined in the splenocytes and bronchoalveolar lavage fluid （BALF）. Serum level of total IgE was also detected. After establishing a mouse allergic rhinitis model with HDM, we have showed that Pam3CSK4 treatment not only ameliorated the nasal allergic symptoms remarkably but also decreased the eosinophils and total inflammation cells in BALF significantly. Analysis of cytokine profile found that IFN-7 released from either BALF or stimulated splenocytes increased markedly in Pam3CSK4-treated mice, while IL-13 decreased significantly. Moreover, serum level of total IgE was significantly lower in Pam3CSK4-treated mice than in the untreated. Thus, in an allergic rhinitis mouse model developed with HDM, Pam3CSK4 was shown to exhibit an antiallergic effect, indicating its potential application in allergic diseases.     

用可调光锥系统获得卫星照片大尺度空间频谱的初步研究

将可调光锥系统直接应用于获得大尺度空间频谱的研究，得到了较满意的实验结果。     

如何设计水库鼻坝的高度与挑角

1　问题的提出水库排放的水流从溢流坝下泄 ,为了减小对坝基的冲击 ,一般用挑流的方法来消除水流的部分动能 ,并使水流形成的冲击力远离坝基 ,以保护水库坝基的安全 .故水流挑离坝基愈远 ,对坝基的安全愈有利 ,因此在修建水库的鼻坝时 ,如何设计好鼻坝的高度与挑角对水库的安全是至关重要的 ,下面我们就这一问题进行探讨 .2　建模与求解图 1如图 1 ,设水库的水位至鼻坝的落差 (即鼻坝的高度 )为ｈ1米 ,鼻坝至坝基的高度为ｈ2米 ,水库大坝总高度为Ｈ(Ｈ =ｈ1+ｈ2 )米 ,鼻坝以下的大坝坡度为ｉ.在不考虑阻力的情况下 ,我们认为水滴汇成水流从…     

测量嗅觉诊断病症的"临床鼻"

如今，一项称为“临床鼻”的医疗产品在新加坡问世，该产品能让医生通过测量人的嗅觉，来诊断出病人是否患上相关疾病，甚至是帕金森症及早老性痴呆症。     

烟酰胺治疗病态窦房结综合症21例疗效观察

鉴于目前临床上对病态窦房结综合症治疗方法不多，我们根据烟酰胺能改善窦房结功能，并能加速房室间传导，故应用烟酰胺治疗21例，取得较好疗效，报告如下：材料与方法病例选择：本组21例中，男性15例，女性6例。年龄21—74岁，平均475岁。病程3个月至7年。全部病例均符合1977年全国病态窦房结综合症诊断标准。治疗前心率40－SO次／分者11例，51－56次／分者IO例。治疗方法：全部病人以俯卧胺加入5％葡萄糖25Oml中静脉滴注，每日一次，ZO次为一疗程c不伍用其它提高心率药物。烟酸胶首次用量为ZOOmg，治疗三天效果不显著者，增至400mg，…     

电信网络系统的远离平衡态特性分析

远离平衡态是电信网络系统有序演化的必要条件,本文从多样性和非均匀性2个方面对电信网络系统的远离平衡态特性进行了分析,从而揭示了电信网络远离平衡态特性和系统有序演化之间的内在逻辑。     

经鼻滴注氟马西尼在小儿门诊手术麻醉后催醒作用的观察

目的观察经鼻滴注氟马西尼对小儿门诊手术麻醉后的催醒作用。方法38例ASAⅠ级的小儿行门诊小手术后随机分为两组,一组经鼻滴注氟马西尼40μg/kg(用药组),另一组不用药(对照组)。结果用药组的麻醉清醒显著短于对照组(P<0.05)。结论40μg/kg氟马西尼用于小儿手术麻醉后,清醒时间可明显缩短。