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动物基因图谱的研究现状及其应用 总被引:2,自引:0,他引:2
随着人类基因组测序的完成,近年来,动物基因组计划也取得了巨大进展.目前已有猪、牛、羊、马、鹿、鸡等动物绘制了较完善的遗传图谱。这些图谱的建立对了解动物整个基因组结构和对家畜中与重要经济性状相关的基因或遗传标记的鉴定及对家畜开展分子标记辅助选择均十分重要,该文从国内外构建动物基因图谱的方法、研究现状及发展趋势等方面对动物基因图谱的研究作了简要阐述;并探讨了其在基因定位、遗传分析、分子标记辅助选择和研究动物染色体行为等方面的应用。 相似文献
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技术的进步,例如电话、电视和互联网,正在改变我们的生活方式,提高我们的生活质量。然而,你有没有想象过在今后5年内和今后20年中,还将会出现哪些与我们生活密切相关的新技术吗?著名的美国巴特勒研究所不仅在技术创新上世界闻名,所做的技术预测也一向被科技界和社会所重视。该研究所分别对2005前和2020年前的战略性技术的发展趋势进行了预测,各列出了前10项最具有战 相似文献
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Genetic and physical finemapping of the Sc locus conferring indica-japonica hybrid sterility in rice (Oryza sativa L.) 总被引:4,自引:0,他引:4
YANGCunyi CHENZhongzheng ZHUANGChuxiong MEIMantong LIUYaoguang 《科学通报(英文版)》2004,49(16):1718-1721
Hybrid sterility is a major hindrance to utilizing the heterosis in indica-japonica hybrids. To isolate a gene Sc conferring the hybrid sterility, the locus was mapped using molecular markers and an F2 population derived from a cross between near isogenic lines. A primary linkage analysis showed that Sc was linked closely with 4 markers on chromosome 3, on which the genetic distance between a marker RG227 and Sc was 0.07 cM. Chromosome walking with a rice TAC genomic library was carried out using RG227 as a starting probe, and a contig of ca. 320 kb covering the Sc locus was constructed. Two TAC clones, M45EI4 and M90J01 that might cover the Sc locus, were partially sequenced. By searching the rice sequence databases with sequences of the TACs and RG227 a japonica rice BAC sequence, OSJNBb0078P24 was identified. By comparing the TAC and BAC sequences, six new PCR-based markers were developed. With these markers the Sc locus was further mapped to a region of 46 kb. The results suggest that the BAC OSJNBb0078P24 and TAC M45EI4 contain the Sc gene. Six ORFs were predicted in the focused 46-kb region. 相似文献
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