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Exposure of cimetidine (CIM) to dry heat (160–180 °C) afforded, upon cooling, a glassy solid containing new and hitherto unknown products. The kinetics of this process was studied by a second order chemometrics-assisted multi-spectroscopic approach. Proton and carbon-13 nuclear magnetic resonance (NMR), as well as ultraviolet and infrared spectroscopic data were jointly used, whereas multivariate curve resolution with alternating least squares (MCR-ALS) was employed as the chemometrics method to extract process information. It was established that drug degradation follows a first order kinetics.  相似文献   
3.
The asymptotic behaviour of a Stokes flow with Tresca free boundary friction conditions when one dimension of the fluid domain tends to zero is studied. A specific Reynolds equation associated with variational inequalities is obtained and uniqueness is proved.  相似文献   
4.
采用建立管芯等效电路模型、灵敏度分析以及统计勘探法对微波单片集成电路进行成品率优化,并编制了软件,加入到GaAsICCAD系统中。应用该软件对X波段低噪声MMIC、超宽带MMIC放大器进行了设计,成品率有较大的提高,电路性能有所改善。  相似文献   
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To validate approximate optimization schemes for estimate calculation algorithms (ECAs), it is necessary to compute the optimal height, which cannot be done in a reasonable amount of time. A variety of samples are built for which the optimal height of the ECAs is known by construction.  相似文献   
7.
M.B. Xu 《Applied Acoustics》2003,64(7):731-752
The forced vibration of an infinite elastic circular cylindrical shell filled with fluid is studied. Three methods are employed to analyze the forced vibration problem of this shell-fluid coupled system, that is, wave propagation approach (wave mode superposition), theorem of residues and a numerical integral method. In order to explain these methods more explicitly, before being used to investigate the vibration of an infinite fluid-filled elastic circular cylindrical shell, all these three methods are employed firstly to analyze the forced vibration problem of an infinite beam and an infinite elastic circular cylindrical shell in vacuo. Advantage and disadvantage of these three methods are discussed and their interesting relationship is revealed. That is, to any circumferential wavenumber and frequency of the external force, there is an unchangeable relationship between the general coordinates of various waves in the wave propagation approach and the residuals in the theorem of residues.  相似文献   
8.
厚高阶光学非线性介质Z扫描的变分法分析   总被引:3,自引:0,他引:3  
利用变分法对具有五阶光学非线性介质的Z扫描特性进行了研究。通过比较,发现当介质在具有较大的五阶非线性系数或较大光强的情况下,五阶非线性项的作用是不可忽略的。这对光限制器的设计和Z扫描实验都具有一定的指导意义。  相似文献   
9.
This is the first part of a work on second order nonlinear, nonmonotone evolution inclusions defined in the framework of an evolution triple of spaces and with a multivalued nonlinearity depending on both x(t) and x(t). In this first part we prove existence and relaxation theorems. We consider the case of an usc, convex valued nonlinearity and we show that for this problem the solution set is nonempty and compact in C^1 (T, H). Also we examine the Isc, nonconvex case and again we prove the existence of solutions. In addition we establish the existence of extremal solutions and by strengthening our hypotheses, we show that the extremal solutions are dense in C^1 (T, H) to the solutions of the original convex problem (strong relaxation). An example of a nonlinear hyperbolic optimal control problem is also discussed.  相似文献   
10.
Two structure functions W1(x,Q2) and W2(x,Q2) are determined by using the cross sections measured in the deep inelastic electron-proton scattering experiments at Stanford Linac in the energy range of 5 to 20 GeV. In this paper an alternative mathematical approach have been used in such determination, resulting in a larger number of points in the graphs of the structure functions.  相似文献   
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