LED生产过程中的质量控制

对LED封装过程可能出现的问题逐一指出，并提出解决的办法，着重介绍封装位置对LED发光亮度的影响。以期引起LED封装管理人员及工作人员的注意。     

Using a process-centered approach to minimize the effort of compliance

 The complexity of different quality standards can, in principle, be covered by different approaches and strategies. In-depth process mapping of quality control (QC) work streams was used by the analytical laboratories of Lonza AG to show up the principle differences in being compliant to different quality systems. The results identified two main drivers for all necessary actions: process-related activities and infrastructure-related activities. In addition, a clear indication of the economic impact of these driving forces was gained, which led the laboratories to decide on a process-oriented approach. This approach has the advantage of being able to reflect the different demands of different quality assurance (QA) regulations within the same QC organizational structure. Following the process helps avoid unnecessary efforts in analytical work and represents a very economical approach, at the same time, providing high flexibility to react to different QA or customer demands. Received: 5 July 2002 Accepted: 12 November 2002 Acknowledgements The process-oriented approach resulted from many, very challenging discussions for which I would like to thank the staff of my organization (Analytics & QC), especially, the QA staff and the LIMS team. Presented at Analytica Conference, 23–26 April 2002, Munich, Germany Correspondence to B. Ciommer     

Three-dimensional interfacial fracture analysis of a one-dimensional hexagonal quasicrystal coating

In this paper, the three-dimensional (3D) interfacial fracture is analyzed in a one-dimensional (1D) hexagonal quasicrystal (QC) coating structure under mechanical loading. A planar interface crack with arbitrary shape is studied by a displacement discontinuity method. Fundamental solutions of interfacial concentrated displacement discontinuities are obtained by the Hankel transform technique, and the corresponding boundary integral-differential equations are constructed with the superposition principle. Green’s functions of constant interfacial displacement discontinuities within a rectangular element are derived, and a boundary element method is proposed for numerical simulation. The singularity of stresses near the crack front is investigated, and the stress intensity factors (SIFs) as well as energy release rates (ERRs) are determined. Finally, relevant influencing factors on the fracture behavior are discussed.     

Ultra high performance liquid chromatography-quadrupole-time of flight analysis for the identification and the determination of resveratrol and its metabolites in mouse plasma

Resveratrol is a polyphenol that has numerous interesting biological properties, but, per os, it is quickly metabolized. Some of its metabolites are more concentrated than resveratrol, may have greater biological activities, and may act as a kind of store for resveratrol. Thus, to understand the biological impact of resveratrol on a physiological system, it is crucial to simultaneously analyze resveratrol and its metabolites in plasma. This study presents an analytical method based on UHPLC-Q-TOF mass spectrometry for the quantification of resveratrol and of its most common hydrophilic metabolites. The use of ¹³C- and D-labeled standards specific to each molecule led to a linear calibration curve on a larger concentration range than described previously. The use of high resolution mass spectrometry in the full scan mode enabled simultaneous identification and quantification of some hydrophilic metabolites not previously described in mice. In addition, UHPLC separation, allowing run times lower than 10 min, can be used in studies that requiring analysis of many samples.     

An automated monitoring system for VOC ozone precursors in ambient air: development,implementation and data analysis

An automated system for the monitoring of volatile organic compound (VOC) ozone precursors in ambient air is described. The measuring technique consists of subambient preconcentration on a cooled trap followed by thermal desorption and GC/FID analysis. First, the technical development, which permits detection limits below 0.05 ppbv to be reached, proceeded in two steps: (1) the determination of optimum sampling parameters (trap composition and conditioning, outlet split, desorption temperature); (2) the development of a reliable calibration method based on a highly accurate standard. Then, a 4-year field application of the hourly measuring chain was carried out at two urban sites. On the one hand, quality control procedures provided the best VOC identification (peak assignment) and quantification (reproducibility, blank system control). On the other hand, the success and performances of the routine experience (88% of the measurements covered more than 40 target compounds) indicated the high quality and suitability of the instrumentation which is actually applied in several French air quality monitoring networks. Finally, an example of data analysis is presented. Data handling identified important organic compound sources other than vehicle exhaust.     

深化全面质量管理五管齐下创“熊猫”名牌

介绍了熊猫电子集团公司以全面质量管理为基础，从产品质量、科技研发、规模经济、服务和市场竞争这五个方面入手，创建熊猫名牌的经验。     

信息化行业的QA和QC的区别和分工

通过在信息化行业中QA和QC的定义和区别,论述QA和QC的主要工作内容,对企业QA和QC部门的分工有一定的借鉴作用。     

Zirconium silicate assisted removal of residual proteins after organic solvent deproteinization of human plasma,enhancing the stability of the LC–ESI-MS response for the bioanalysis of small molecules

An efficient blood plasma clean-up method was developed, where methanol protein precipitation was applied, followed by zirconium silicate assisted exclusion of residual proteins. A strong binding of zirconium (IV) silicate to the proteins enabled the elimination of remaining proteins after solvent deproteinization through a rapid solid-phase extraction (SPE) procedure. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI/TOF MS) was used for monitoring the proteins during clean-up practice applied to human plasma samples. The proteins were quantified by colorimetric detection using the bicinchoninic acid (BCA) assay. The presented analytical strategy resulted in the depletion of >99.6% proteins from human plasma samples. Furthermore, high-performance liquid chromatography hyphenated to diode-array and electrospray ionization mass spectrometric detection (HPLC–DAD/ESI MS) was applied for qualitative and quantitative analysis of the caffeoylquinic acids (CQAs) and their metabolites in human plasma. The procedure demonstrated high recoveries for the standard compounds spiked at different concentrations. Cynarin and chlorogenic acid were recovered in the range of 81–86% and 78–83%, respectively. Caffeic acid was extracted in the excess of 89–92%, while ferulic acid and dihydroxyhydrocinnamic acid showed a recovery of 87–91% and 92–95%, respectively. The method was partially validated in accordance with FDA-Industry Guidelines for Bioanalytical Method Validation (2001). The presented scheme improves the clean-up efficacy of the methanol deproteinization, significantly reduces the matrix effects and provides a great analytical tool for the isolation of small molecules from human plasma.     

Construction of quasi‐cyclic low‐density parity‐check codes with low encoding complexity

Low encoding complexity is very important for quasi‐cyclic low‐density parity‐check (QC‐LDPC) codes used in wireless communication systems. In this paper, a new scheme is presented to construct QC‐LDPC codes with low encoding complexity. This scheme is called two‐stage particle swarm optimization (TS‐PSO) algorithm, in which both the threshold and girth distribution of QC‐LDPC codes are considered. The proposed scheme is composed of two stages. In the first stage, we construct a binary base matrix of QC‐LDPC code with the best threshold. The matrix is constructed by combining a binary PSO algorithm and the protograph extrinsic information transfer (PEXIT) method. In the second stage, we search an exponent matrix of the QC‐LDPC code with the best girth distribution. This exponent matrix is based on the base matrix obtained in the first stage. Consequently, the parity‐check matrix of the QC‐LDPC code with the best threshold and best girth distribution are constructed. Furthermore, bit error rate performances are compared for the QC‐LDPC codes constructed by proposed scheme, the QC‐LDPC code in 802.16e standard, and the QC‐LDPC code in Tam's study. Simulation results show that the QC‐LDPC codes proposed in this study are superior to both the 802.16e code and the Tam code on the additive white Gaussian noise (AWGN) and Rayleigh channels. Moreover, proposed scheme is easily implemented, and is flexible and effective for constructing QC‐LDPC codes with low encoding complexity. Copyright © 2012 John Wiley & Sons, Ltd.     

一种USB加密卡的设计

提出了一种基于USB(通用串行总线)接口的加密卡的设计方案，对USB处理器AN2131QC的软硬件设计，提供给用户端调用的DLL(动态键接库)函数的设计以及驱动程序的设计进行了介绍。系统为用户设计软件保护密码验证功能的实现提供了一种较好的解决方案，即插即用，具有一定的实用价值。