Detecting Extended Technicolor Effects via the Process e^＋e^—→tt^— at High Energy e^＋e^—,Linear Collider

We calculate the corrections of extended technicolor(ETC) interactions to the asymmetry parameter ALR and the polarized parameters PL^t,PR^t of the process e^ e^-→tt- in topcolor-assisted multiscale technicolor model.our results show that the ETC efect effect on PR^t in negligibly small which can be safely ignored,and the ETC effect on ALR may be testable at high energy e^ e^- linear collider(LC),FOr 0.03≤ε≤0.1,500GeV≤s○800GeV,the relative correction of PL^t is in the range of 15%≤δPL^t/PL^t,SM≤39%,which will certainly be detected at the LC experiments(for example TESLA).     

跳频分组无线网的路由算法分析

跳频分组无线网抗干扰性好,保密性强,广泛应用于战术通信系统。讨论了几种跳频分组无线网的路由选择算法,着重分析了针对传输多类型分组跳频网的ALR路由算法,并将此路由算法的性能与DAR算法的性能进行了比较,证实了该算法在吞吐量、端-端正确传输率等方面都优于传统的方法。     

一种新型喷嘴的提出及流量特性的研究

本文在对各种气动喷嘴及其雾化机理分析基础上提出了一种新型的气动雾化喷嘴-"旋转型气-液雾化喷嘴"。在此喷嘴中,油与气分别从不同的槽道切向进入混合室,且油与气一一对应,油与气互相混合、旋转后从喷口喷出。其气液比在热态实验时为4%-6%(用压缩空气雾化),雾化状态良好。本文中对其流量系数及雾化角进行了系统的研究。主要考虑了喷嘴的结构参数,气液比(ALR),液体粘度等因素对流量系数的影响。通过实验测量与拟合,最后得到了喷嘴的流量系数和雾化角的表达式,可以用来指导喷嘴的设计。     

Integrated pharmacophore and docking‐based designing of dual inhibitors of aldose reductase (ALR2) and protein tyrosine phosphatase 1B (PTP1B) as novel therapeutics for insulin‐resistant diabetes and its complications

The dual inhibitors against aldose reductase (ALR2) and protein tyrosine phosphatase 1B (PTP1B) may present an anti‐diabetic potency in insulin resistance without risks of serious diabetic complications. Therefore, in the present study, we constructed two separate pharmacophore mapping‐based 3D quantitative structure–activity relationship models for ALR2 (AADRR.1109₃ with standard deviation 0.663, 0.719, F 22.3, root‐mean‐square error 0.705, 0.647, Pearson‐r 0.802) and PTP1B (AARR.15₅ with standard deviation 0.146, 0.945, F 82.70, root‐mean‐square error 0.351, 0.621, Pearson‐r 0.831) employing the dataset of 54 flavonoids as ALR2 inhibitors and 46 naphthoquinones as PTP1B inhibitors to identify structural features necessary for the inhibition of both enzymes. These models were subsequently used as 3D query search for hierarchical virtual screening‐based designing using the PHASE database of 1.5 million compounds. Designed dual inhibitors were further subjected to GLIDE XP docking analysis using high‐resolution 3D structures of ALR2 (1US0, at resolution of 0.66 Å) and PTP1B (2F71 at resolution of 1.55 Å) available in the Protein Data Bank to authenticate identified structural features with important binding interactions necessary for dual inhibition. Copyright © 2014 John Wiley & Sons, Ltd.