排序方式: 共有71条查询结果,搜索用时 31 毫秒
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原子力与光子扫描隧道组合显微镜 总被引:3,自引:0,他引:3
介绍了超高分辨光于扫描隧遭显微镜(PSTM)的计冗历程,为解决第一代(单光束照明)光千扫捕隧逼显傲镜中存在人为假象和样品光学图像与形貌图像难于分离两个难题,用“对称双光束照明方法消假象,用原子力与光子扫描隧道组合显微镜(AF/PSTM)图像分解方法分离样品光学透过率、折射率与形貌图像。研制成功新一代原子力与光子扫描隧道组合显微镜(AF/PSTM)样机。该样机在一次扫描中已获得两幅原子力显微镜图像(形貌与相位)和两幅光学图像(透过率和折射率),有效地减少了假象,分解了样品光学折射率、透过率与形貌图像。 相似文献
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湍流大气中图像传输的信息量 总被引:1,自引:1,他引:0
分别从系统像的信息量和信息自由度的角度分析了大气湍流对相干和不相干照明光学系统成像质量和分辨率的影响。理论上,处于一定大气湍流条件下的相干照明系统存在着超出经典衍射极限的超分辨率。 相似文献
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Conventional phase diffraction gratings can be used to localize the incoming optical radiation in the near‐field region. A new design of the binary phase diffraction grating is proposed with embedded pupil opaque mask inside each stripe. By means of numerical simulations, it is shown that with this masked phase grating the spatial resolution of the near‐field localization can be substantially improved and brought even beyond the solid immersion limit (λ/2n). Moreover, due to anomalous apodization effect, the subdiffraction field localization is accompanied by intensity enhancement as compared to the non‐masked design. The pupil mask rearranges the optical fluxes within the stripes and promotes the Fano resonances excitation in the periodic step lattice. This can be important for advancing the phase grating‐based super‐resolution technologies, including subdiffraction imaging, interferometry, and surface fabrication. 相似文献
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Daniel L. Farkas 《Molecules (Basel, Switzerland)》2021,26(21)
Light is a powerful investigational tool in biomedicine, at all levels of structural organization. Its multitude of features (intensity, wavelength, polarization, interference, coherence, timing, non-linear absorption, and even interactions with itself) able to create contrast, and thus images that detail the makeup and functioning of the living state can and should be combined for maximum effect, especially if one seeks simultaneously high spatiotemporal resolution and discrimination ability within a living organism. The resulting high relevance should be directed towards a better understanding, detection of abnormalities, and ultimately cogent, precise, and effective intervention. The new optical methods and their combinations needed to address modern surgery in the operating room of the future, and major diseases such as cancer and neurodegeneration are reviewed here, with emphasis on our own work and highlighting selected applications focusing on quantitation, early detection, treatment assessment, and clinical relevance, and more generally matching the quality of the optical detection approach to the complexity of the disease. This should provide guidance for future advanced theranostics, emphasizing a tighter coupling—spatially and temporally—between detection, diagnosis, and treatment, in the hope that technologic sophistication such as that of a Mars rover can be translationally deployed in the clinic, for saving and improving lives. 相似文献
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利用matlab优化工具箱,采用非线性规划,对三区振幅型(透过率为1-0-1)和三区位相型(相位角为π-0-π)光瞳滤波器进行三维超分辨优化设计,建立了优化模型,经计算机多次迭代运算,改变斯特尔比s值,给出了优化结果.结果显示:所设计的滤波器较好地实现了横向和轴向三维超分辨,且轴向超分辨能力优于横向;相同斯特尔比下,位相型三维超分辨能力优于振幅型,并且这两种滤波器结构简单,容易实现. 相似文献
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正弦变化的振幅型光瞳滤波器 总被引:6,自引:0,他引:6
光瞳滤波器作为实现超分辨的基本元件之一,它的设计以及制作都非常重要。设计了一种正弦变化的振幅型光瞳滤波器,可以通过调节少量的参量实现各种不同的超分辨模式。选择正弦函数的周期以及光瞳中心点透过率变化两个参量来实现对最终超分辨效果的调节。数值计算结果表明:在整个人射光瞳上的透过率瞳函数分布具有0.5~2个正弦振幅周期时,较为合适。小于0.5个周期将不会有任何超分辨效果,大于2个周期超分辨效果反而变差。数值计算中还注意到,当周期数为整数时,斯特雷尔比将保持0.25不变。对正弦变化振幅型光瞳滤波器的计算结果,显示了其特殊的性质,对实际中制作正弦变化振幅型光瞳滤波器有一定的指导作用。 相似文献
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径向双折射滤波器的超分辨性能研究 总被引:4,自引:3,他引:1
超分辨技术因其可以超越经典的衍射极限而为人们所熟知.并且.在光存储和共焦扫描成像系统中有着广泛的应用。把由两个偏振器和一个圆对称的双折射元件组成的径向双折射滤波器引入超分辨技术,借助琼斯算法推导出其光瞳函数的表达式。由分析得出通过改变径向双折射滤波器中偏振器的偏振方向和双折射元件的主轴之间的夹角,即可实现光学系统的横向超分辨或轴向超分辨。同时对评价该器件超分辨性能的参量第一零点比、斯特尔比和旁瓣强度抑制比做了详细的讨论。该滤波器用于超分辨技术的优点在于其制作不涉及相位的变化而比较简单,且费用比较低。缺点是旁瓣能量过高,但可以通过采用共焦系统来抑制。 相似文献