X-Y振镜扫描式舌诊高光谱采集系统

针对目前舌诊研究中在舌体信息全面获取方面存在严重不足,将高光谱技术用到舌诊的研究中来,提出了一种基于X-Y振镜扫描式舌诊高光谱采集系统.通过模拟实验,采集与舌体大小相似图片的高光谱信息,验证了该系统可以用于舌体高光谱信息采集,实验结果表明,与现有舌诊客观化研究相比,该系统可以获得更多的舌体信息,为舌诊客观化研究提供了一...     

舌体高光谱的高血压患者中合并冠心病的筛查方法

高血压合并冠心病是高血压疾病的一类严重合并症.目前高血压患者对合并冠心病的情况检测不及时,容易导致严重事件的发生,其致残率、致死率极高,严重影响患者的生活质量.因此对高血压患者合并冠心病的早期发现对预防更严重事件的发生显得尤为重要.舌体信息与心血管功能关系密切,为此,提出一种基于舌体高光谱用于高血压患者中合并冠心病筛查...     

一体式中医舌象采集分析系统设计

舌象采集是中医舌象分析中非常重要的一环,一套稳定、可靠、高精度的舌象采集系统直接影响到舌象分析和病情诊断的准确性。针对上述要求,设计了一种一体式的中医舌象采集分析系统,具有结构简单,功能全面,体积小等特点。通过积分球搭建的光照环境保证了舌体的受光均匀。使用MFC编写采集处理程序,便于升级维护。研究了一种手动调节相机白平衡参数的方法,保证采集过程中舌象颜色的准确性。     

双波长比值光谱差异度指数用于人体舌苔舌质分离

舌苔舌质信息定量描述作为中医舌诊的重要内容,直接影响到中医临床舌诊的准确性。基于生物医学光子学理论,利用高光谱技术,提出一种基于双波长比值光谱差异度指数进行人体舌质舌苔分离的光谱分析新方法。首先采集被测对象371.200～992.956 nm之间共343个波长的舌体高光谱信息,随机选取15位被测对象进行光谱特征分析。绘制15位被测对象舌质舌苔全波段光谱曲线并进行比较,通过观察发现,舌质舌苔反射光特征差异与血红蛋白在该波段的光学特征变化相吻合,在500～750 nm之间,水对光的吸收很少,而舌体表面布满血管,光的吸收主要受到血红蛋白的影响,基于舌质舌苔在573和700 nm两波段光谱吸收差异,计算双波长比值,提取舌质舌苔光谱特征差异度指数,根据个体差异,分别提取不同被测对象舌质舌苔光谱特征差异指标,进行舌质舌苔区域分离,实验结果发现,对同一被测对象舌体苔质提取光谱差异度指数SDI,舌苔舌质光谱差异度指数存在一定差异性,由于个体的不同,具有各自明显的舌质、舌体差异度指数分割线,实验结果表明,运用双波长比值光谱差异度指数的光学表达形式能够用于舌质舌苔分离,同时该方法也能够为进一步中医临床舌诊提供客观依据。     

血细胞压积与平均血红蛋白浓度的可见-近红外光谱无创检测

血细胞压积和平均血红蛋白浓度的检测对于心脑血管疾病以及贫血等疾病的预防和治疗起着非常重要的作用,为了能够无创、准确的对血细胞压积和平均血红蛋白浓度进行检测,本研究提出了一种基于光谱技术的检测方法。经解剖学研究表明,在微循环中,血流变的异常以及血液粘稠度的改变均能引起舌象的变化,即舌象和血液成分之间存在一定的相关性,所以本研究通过采集240例志愿者舌尖反射光谱,同时拍摄志愿者舌体图片和记录生化分析结果。在进行数学建模前,首先将240例志愿者随机分为校正集和验证集,运用偏最小二乘分别建立数学模型,校正集预测值和生化分析真实值之间相关系数分别为0.998和0.938,运用所建数学模型对验证集未知样本进行预测,验证集未知样本的预测结果与生化分析真实值之间相关系数分别为0.979和0.883,平均相对误差分别为1.65%和1.88%,均方根误差分别为4.066和4.139,由实验结果可见,所建立的模型可以较好的对HCT和MCHC进行预测,同时实验结果也表明近红外光谱分析结合偏最小二乘方法有可能能够为血细胞压积和平均血红蛋白浓度的检测提供一种无创的检测方法。     

电子舌及其在饮料区分辨识方面研究进展

电子舌技术是20世纪80年代中期发展起来的一种分析、识别液体味道的新型检测手段.它与普通化学仪器不同,得到的不是被测样品中的某种或某几种成分的定性或是定量结果,而是样品成分的整体信息.本文介绍了电子舌的工作原理及其在饮料区分辨识中的研究进展,并对电子舌的发展和趋势作了展望.     

M-Mode Color Doppler Ultrasonic Imaging of Vertical Tongue Movement During Articulatory Movement

To observe and estimate the movement of the tongue, ultrasonic investigation is the most harmless real-time monitoring procedure for analyzing articulatory movements. Color Doppler ultrasonic imaging is special in that it can only sample a moving target, and it can indicate the velocity and direction of the target by color and brightness in real time. This study assessed and demonstrated the validity of M-mode color Doppler ultrasonic imaging to observe the movements of the tongue during syllable repetition tasks performed by normal subjects and dysarthric patients, those affected by amyotrophic lateral sclerosis, cerebellar ataxia, Parkinsonism, and polymyopathy. When the transducer was set below the jaw, upward movement was indicated by a blue signal and downward movement was indicated by a red one on the screen of the ultrasound machine. We also measured the velocity of the tongue by contrast scale classified by 15 degrees. Thus, we could observe vertical tongue movement by a color-coded pattern after quantitative analysis. The Doppler signal patterns of normal subjects were verified by simultaneous video x-ray fluorography recordings. The findings for dysarthric patients corresponded well with previously reported features analyzed by other methods. Therefore, color Doppler ultrasonic imaging of the tongue is a useful procedure to researchers for clinical speech and voice studies.     

Vocal and Laryngeal Effects of Voiced Tongue Vibration Technique According to Performance Time

Our objective is to study the vocal and laryngeal effect as well as the negative signs and sensations related to the voiced tongue vibration technique (VTVT), regarding the time of performance (from 0 to 7 minutes). Thirty adults (15 men and 15 women) with no vocal complaints nor laryngeal disorders were involved. All subjects underwent laryngostroboscopic and auditory perceptual analysis and answered about the existence of uncomfortable sensations that occurred during the exercise (1, 3, 5, and 7 minutes) and postexercise. For the auditory perceptual analysis, the female group presented better outcomes in the third minute of exercise, whereas in general the male group showed no modification because of performance time. Some men presented a significant change in the parameters involved from the fifth minute on. Men and women showed a gradual increase of undesirable sensations. It is extremely important that the performance time of the VTVT is properly prescribed to provide the expected results, without causing undue injuries to the vocal system. Therefore, we suggest this technique should be recommended for 3 and 5 minutes for women and men, respectively.     

光调制技术用于提高光谱法舌诊的测量信噪比

为了解决光谱采集受环境光干扰严重的问题,首次将光调制技术用于提高光谱法舌诊测量的信噪比。系统采用调制盘对参考光信号强度进行调制,运用此装置采集同一被测体在分别叠加绿色、紫色、红色激光以及自然环境光干扰情况下的反射光谱,对采集来的数据运用离散傅里叶变换进行解调,提取最大谐波分量,然后对提取的最大谐波分量进行归一化,绘制解调后的光谱曲线,通过比较发现,不同干扰情况下所测同一被测体经过调制解调后的反射光谱曲线走向基本一致,结果表明光调制技术能够去除舌体反射光谱采集中环境杂散光的干扰,为高信噪比舌诊光谱数据采集提供了一种新途径。