Endoscopic Observation of Tissue by Narrowband Illumination

We propose a new illumination method for a medical endoscope: narrow band imaging (NBI), in which the spectral bandwidth of the filtered light is narrowed. To confirm how the spectral specifications of the filtered light influence a reproduced image, an experiment was conducted observing the endoscopic images of the back mucosa of a human tongue. In addition, the effect of NBI on endoscopic images was investigated through preliminary clinical tests in colonoscopy and upper gastrointestinal endoscopy. It has been shown that NBI can enhance the capillary pattern and the crypt pattern on the mucosa. These patterns are useful features for diagnosing an early cancer.     

Magneto-responsive nanocomposites: Preparation and integration of magnetic nanoparticles into films,capsules, and gels

This review reports on the latest developments in the field of magnetic nanocomposites, with a special focus on the potentials introduced by the incorporation of magnetic nanoparticles into polymer and supramolecular matrices. The general notions and the state of the art of nanocomposite materials are summarized and the results reported in the literature over the last decade on magnetically responsive films, capsules and gels are reviewed. The most promising concepts that have inspired the design of magneto-responsive nanocomposites are illustrated through remarkable examples where the integration of magnetic nanoparticles into organic architectures has successfully taken to the development of responsive multifunctional materials.     

天然植物高分子药用胶囊的研究与发展

讨论了天然植物高分子药用胶囊的最新研究与发展,介绍了目前的主要研究成果并提出展望.不仅从化学结构、流变和相变等基础理论方面探讨了各类植物药用胶囊的特性和研制中所遇到的问题,同时对各种胶囊制备设备与工艺的发展及应用中的技术改进进行了综述分析.传统明胶胶囊生产工艺的应用已有160多年的历史,目前植物胶囊生产设备和工艺多是建立在传统明胶胶囊生产的基础上.研究植物胶囊材料的流变和凝胶性能以尽量满足传统明胶的设备与工艺是当今急需解决的难题之一.近年来,随着人们对淀粉结构和改性方法的深入研究(尤其是将淀粉基可生物降解材料的制备技术与传统食品科学的研究成果有效结合),应用高分子科学理论和方法提高淀粉基材料的加工性能,力学性能与稳定性的研究有了突破性进展,为淀粉胶囊的研制提供了理论和技术上的有力支持.使用传统塑料加工的挤出加工法制备植物胶囊,是植物胶囊研究中的重大突破和创新.从原材料来源的充足性和价格上考虑,淀粉是最有潜力替代传统胶囊的原料之一.     

可调焦胶囊内窥镜光学系统设计

为解决胶囊内窥镜分辨率与景深相互制约的问题,将一种单液体、电控、可变焦液体透镜应用到内窥镜光学系统中进行光学设计,在保证分辨率的同时,扩大了系统景深.采用CODE V软件进行设计,建立系统初始结构,构造液体透镜模型,基于液体透镜中液体的体积不变,曲率、孔径和厚度可变的结构约束特点,在MATLAB中计算出不同物距下透镜的曲率、孔径和厚度数据,将其导入CODE V的系统模型中,并提出了相应的优化流程.设计并优化带有液体透镜的胶囊内窥镜系统,实现了系统在3~100mm景深范围内的清晰成像,视场角大于110°,全视场范围内调制传递函数在40lp/mm频率下均大于0.3.     

Numerical solutions of peristaltic flow of Williamson fluid with radially varying MHD in an endoscope

In this article we have studied the peristaltic motion of an incompressible Williamson fluid with constant and radially varying magnetohydrodynamics (MHD) in an endoscope. Using the low Reynolds and long wavelength assumptions, the equations of Williamson fluid model in simplified form are solved using (i) the HAM method and (ii) the Shooting method. The comparisons of both solutions have been found a very good agreement. Graphical results have been presented for various emerging parameters. © British Crown Copyright 2010/MOD. Reproduced with permission. Published by John Wiley & Sons, Ltd.     

具有图象处理功能的激光荧光内窥系统的研究

内窥镜荧光图象系统是体腔内早期肿瘤诊断和定位的有效手段.但是早期开发研究的LFE荧光成家系统由于存在假阳性和假阴性误诊而限制了它的广泛开展和应用.本文仔细探讨了该系统产生误诊的原因,并在此基础上提出了使用计算机图象处理技术的荧光图象系统,而且通过实验验证了这种新技术,它能有效地克服假阳性和假阴性误诊,为体腔内肿瘤的诊断提供可靠判据.     

利用海藻酸钙胶囊提取醋酸

我们曾进行了利用聚酰胺胶囊处理含铬废水的研究,取得了一些结果,积累了一定的经验.当前还没有找到从低浓度的醋酸废水溶液中提取醋酸的有效方法.戴猷元等人曾用中空纤维膜器中萃取方法处理低浓度的醋酸水溶液.本文利用内含磷酸三丁酯(TBP)的海藻酸钙胶囊处理低浓度的醋酸水溶液.实验表明,这种方法与利用萃取剂直接萃取法相比有明     

胃康灵胶囊中15种元素含量分析

微波消解法制备供试品,电感耦合等离子体-质谱(ICP-MS)法测定中成药胃康灵胶囊中15种元素的含量,探讨其宏量、微量元素与疗效的关系。胃康灵胶囊中常量元素含量丰富,微量元素含量差别较大,Fe含量最多,Se含量最少,有害元素含量不高。胃康灵胶囊中元素与胃炎及胃溃疡的治疗密切相关。     

An analytical and numerical study of peristaltic transport of a Johnson-Segalman fluid in an endoscope

In the present study, we discuss the peristaltic flow of a Johnson-Segalman fluid in an endoscope. Perturbation, homotopy, and numerical solutions are found for the non-linear differential equation. The comparative study is also made to check the validity of the solutions. The expressions for pressure rise frictional forces, pressure gradient, and stream lines are presented to interpret the behavior of various physical quantities of the Johnson-Segalman fluid.