模糊线性回归模型的约束最小二乘估计

自Tanaka等1982年提出模糊回归概念以来,该问题已得到广泛的研究。作为主要估计方法之一的模糊最小二乘估计以其与统计最小二乘估计的密切联系更受到人们的重视。本文依据适当定义的两个模糊数之间的距离,提出了模糊线性回归模型的一个约束最小二乘估计方法,该方法不仅能使估计的模糊参数的宽度具有非负性而且估计的模糊参数的中心线与传统的最小二乘估计相一致。最后,通过数值例子说明了所提方法的具体应用。     

Molecular dynamics and information on possible sites of interaction of intramyocellular metabolites in vivo from resolved dipolar couplings in localized H NMR spectra

Proton NMR resonances of the endogenous metabolites creatine and phosphocreatine ((P)Cr), taurine (Tau), and carnosine (Cs, β-alanyl-l-histidine) were studied with regard to residual dipolar couplings and molecular mobility. We present an analysis of the direct ¹H–¹H interaction that provides information on motional reorientation of subgroups in these molecules in vivo. For this purpose, localized ¹H NMR experiments were performed on m. gastrocnemius of healthy volunteers using a 1.5-T clinical whole-body MR scanner. We evaluated the observable dipolar coupling strength SD₀ (S = order parameter) of the (P)Cr-methyl triplet and the Tau-methylene doublet by means of the apparent line splitting. These were compared to the dipolar coupling strength of the (P)Cr-methylene doublet. In contrast to the aliphatic protons of (P)Cr and Tau, the aromatic H2 (δ = 8 ppm) and H4 (δ = 7 ppm) protons of the imidazole ring of Cs exhibit second-order spectra at 1.5 T. This effect is the consequence of incomplete transition from Zeeman to Paschen-Back regime and allows a determination of SD₀ from H2 and H4 of Cs as an alternative to evaluating the multiplet splitting which can be measured directly in high-resolution ¹H NMR spectra. Experimental data showed striking differences in the mobility of the metabolites when the dipolar coupling constant D₀ (calculated with the internuclear distance known from molecular geometry in the case of complete absence of molecular dynamics and motion) is used for comparison. The aliphatic signals involve very small order parameters S ≈ (1.4 − 3) × 10⁻⁴ indicating rapid reorientation of the corresponding subgroups in these metabolites. In contrast, analysis of the Cs resonances yielded S ≈ (113 − 137) × 10⁻⁴. Thus, the immobilization of the Cs imidazole ring owing to an anisotropic cellular substructure in human m. gastrocnemius is much more effective than for (P)Cr and Tau subgroups. Furthermore, ¹H NMR experiments on aqueous model solutions of histidine and N-acetyl-l-aspartate (NAA) enabled the assignment of an additional signal component at δ = 8 ppm of Cs in vivo to the amide group at the peptide bond. The visibility of this proton could result from hydrogen bonding which would agree with the anticipated stronger motional restriction of Cs. Referring to the observation that all dipolar-coupled multiplets resolved in localized in vivo ¹H NMR spectra of human m. gastrocnemius collapse simultaneously when the fibre structure is tilted towards the magic angle (θ ≈ 55°), a common model for molecular confinement in muscle tissue is proposed on the basis of an interaction of the studied metabolites with myocellular membrane phospholipids.     

Gray code for derangements

We give a Gray code and constant average time generating algorithm for derangements, i.e., permutations with no fixed points. In our Gray code, each derangement is transformed into its successor either via one or two transpositions or a rotation of three elements. We generalize these results to permutations with number of fixed points bounded between two constants.     

关于限制李超代数的分解

代数$A$ 称为不可分解的,如果 $A$ 不能分解成理想的直和.文中将证明满足$C(L_{\bar{0}})=C(L)=\{0\}$的限制李超代数能够分解成不可分解限制理想的直和,这种分解在不计理想次序的前提下是唯一的.而且还证明了限制李超代数的一些结果.     

Solving a multiobjective location routing problem with a metaheuristic based on tabu search. Application to a real case in Andalusia

In this work we present a multiobjective location routing problem and solve it with a multiobjective metaheuristic procedure. In this type of problem, we have to locate some plants within a set of possible locations to meet the demands of a number of clients with multiple objectives. This type of model is used to solve a problem with real data in the region of Andalusia (Spain). Thus, we study the location of two incineration plants for the disposal of solid animal waste from some preestablished locations in Andalusia, and design the routes to serve the different slaughterhouses in this region. This must be done while taking into account certain economic objectives (start-up, maintenance, and transport costs) and social objectives (social rejection by towns on the truck routes, maximum risk as an equity criterion, and the negative implications for towns close to the plant).     

Location of terror response facilities: A game between state and terrorist

We study a leader follower game with two players: a terrorist and a state where the later one installs facilities that provide support in case of a terrorist attack. While the Terrorist attacks one of the metropolitan areas to maximize his utility, the State, which acts as a leader, installs the facilities such that the metropolitan area attacked is the one that minimizes her disutility (i.e., minimizes ‘loss’). We solve the problem efficiently for one facility and we formulate it as a mathematical programming problem for a general number of facilities. We demonstrate the problem via a case study of the 20 largest metropolitan areas in the United States.     

Practical aspects associated with location planning for maternal and perinatal assistance in Brazil

A study has been carried out aimed at reducing perinatal mortality in the municipality of Rio de Janeiro through a better distribution of health care facilities. The algorithmic aspects are detailed elsewhere and here the emphasis is on practical issues and difficulties encountered. A 3-level hierarchical model was developed. Both uncapacitated and capacitated versions are briefly described together with some results based on actual data. The project brought to light many contradictions between OR theory and practice in developing countries and, unfortunately, the models developed were not implemented by the municipality health authorities. Possible reasons for this outcome are analysed.     

Identifying phylogenetic trees

A central problem that arises in evolutionary biology is that of displaying partitions of subsets of a finite set X on a tree whose vertices are partially labelled with the elements of X. Such a tree is called an X-tree and, for a collection of partitions of subsets of X, characterisations for the existence and uniqueness of an X-tree that displays have been previously given in terms of chordal graphs. In this paper, we obtain two closely related characterisations also in terms of chordal graphs. The first describes when identifies an X-tree, and the second describes when a compatible subset of is of maximum size.     

SEQUENTIAL QUADRATIC PROGRAMMING METHODS FOR OPTIMAL CONTROL PROBLEMS WITH STATE CONSTRAINTS

A Kind of direct methods is presented for the solution of optimal control problems with state constraints.These methods are sequential quadratic programming methods.At every iteration a quadratic programming which is obtained by quadratic approximation to Lagrangian function and Linear approximations to constraints is solved to get a search direction for a merit function.The merit function is formulated by augmenting the Lagrangian funetion with a penalty term.A line search is carried out along the search direction to determine a step length such that the merit function is decreased.The methods presented in this paper include continuous sequential quadratic programming methods and discreate sequential quadrade programming methods.     

The restricted Grassmannian, Banach Lie-Poisson spaces, and coadjoint orbits

We investigate some basic questions concerning the relationship between the restricted Grassmannian and the theory of Banach Lie-Poisson spaces. By using universal central extensions of Lie algebras, we find that the restricted Grassmannian is symplectomorphic to symplectic leaves in certain Banach Lie-Poisson spaces, and the underlying Banach space can be chosen to be even a Hilbert space. Smoothness of numerous adjoint and coadjoint orbits of the restricted unitary group is also established. Several pathological properties of the restricted algebra are pointed out.