Compounds with inhibitory activity on peristalsis from the seeds of Holarrhena antidysenterica

Eight compounds were isolated from the seeds of Holarrhena antidysenterica Wall.ex A.DC. On the basis of physico-chemical properties and spectroscopic data, holarrhenanan (1) was identified as a new compound, compounds 2–3 were isolated from H. antidysenterica for the first time, and five known compounds were also obtained. Inhibitory effects of some compounds and extracts to the intestinal peristalsis were evaluated. Results showed that the extracts and compounds 4, 6 exhibited remarkable inhibitory effects with tension inhibition rate of 32.77, 32.77% and amplitude inhibition rate of 59.51, 55.98%, respectively on the vitro rabbit intestinal peristalsis.     

Peristatcally induced MHD slip flow in a porous medium due to a surface acoustic wavy wall

The influences of Hall current and slip condition on the MHD flow induced by sinusoidal peristaltic wavy wall in two dimensional viscous fluid through a porous medium for moderately large Reynolds number is considered on the basis of boundary layer theory in the case where the thickness of the boundary layer is larger than the amplitude of the wavy wall. Solutions are obtained in terms of a series expansion with respect to small amplitude by a regular perturbation method. Graphs of velocity components, both for the outer and inner flows for various values of the Reynolds number, slip parameter, Hall and magnetic parameters are drawn. The inner and outer solutions are matched by the matching process. An interesting application of the present results to mechanical engineering may be the possibility of the fluid transportation without an external pressure.     

Influence of slip condition on the peristaltic transport in an asymmetric channel with heat transfer: An exact solution

The mechanism of peristaltic magnetohydrodynamic (MHD) flow based on slip and heat transfer effects is studied in an asymmetric channel. An incompressible viscous fluid fills the porous space inside the channel. Long wavelength and zero Reynolds number approximation are used in the flow modeling. Expressions of stream function, longitudinal pressure gradient, and temperature are developed. Various interesting phenomena associated with peristalsis, such as pumping and trapping, are discussed in detail. Further the effects of various pertinent parameters on temperature field and heat transfer coefficient are explained with the help of graphs and tables. It is found that pressure rise over one wavelength decreases in pumping region for large values of slip parameter. Similar behavior is observed for temperature field by increasing the slip parameter. However, the volume of trapped bolus decreases by increasing the slip parameter. Copyright © 2010 John Wiley & Sons, Ltd.     

Effect of homogeneous and heterogeneous chemical reactions on peristaltic transport of an MHD micropolar fluid with wall effects

In this paper, the influence of magnetic field on the dispersion of a solute in peristaltic flow of an incompressible micropolar fluid is studied as a model of fluid transport in the human intestinal system with wall properties. Long wavelength approximation, Taylor's limiting condition, and dynamic boundary conditions at the flexible walls are used to obtain the average effective dispersion coefficient in the presence of combined homogeneous and heterogeneous chemical reactions. The effects of various pertinent parameters on the effective dispersion coefficient are discussed. Average effective dispersion coefficient increases with amplitude ratio, which implies that dispersion is more in the presence of peristalsis. It also increases with the cross‐viscosity coefficient, heterogeneous chemical reaction rate, and wall parameters. Further, dispersion decreases with micropolar parameter, magnetic parameter, and homogeneous chemical reaction rates. Copyright © 2015 John Wiley & Sons, Ltd.     

Hall and ion slip effects on peristaltic flow and heat transfer analysis with Ohmic heating

The peristaltic transport of a magnetohydrodynamic （MHD） fluid is exam- ined for both symmetric and asymmetric channels. Hall and ion slip effects are taken into account. The heat transfer is analyzed by considering the effects of viscous and Ohmic dissipations. The relevant flow problems are first modeled, and then the closed form solutions are constructed under the assumptions of long wavelength and low Reynolds number. The solutions are analyzed through graphical illustration. It is noted that the velocity increases but the temperature decreases with the increases in the Hall and ion slip parameters. The axial pressure gradient is less in magnitude in the presence of Hall and ion slip currents. The Hall and ion slip effects are to decrease the maximum pres- sure against which peristalsis works as a pump. The free pumping flux decreases with the increases in the Hall and ion slip parameters. The increases in the Hall and ion slip parameters result in an increase in the size of the trapped bolus.     

Physiological Transportation of Casson Fluid in a Plumb Duct

This paper is devoted to a study of the peristaltic motion of a Casson fluid of a non-Newtonian fluid accompanied in a horizontai tube.To characterize the non-Newtonian fluid behavior,we have considered the Casson fluid model.Suitable similarity transformations are utilized to transform the governing partial differential momentum into the non-linear ordinary differential equations.Exact analytical solutions of these equations are obtained and are the properties of velocity,pressure and profiles are then studied graphically.     

Variable viscosity in peristalsis of Sisko fluid

This paper aims to examine variable viscosity effects on peristalsis of Sisko fluids in a curved channel with compliant characteristics. Viscous dissipation in a heat transfer is studied. The resulting problems are solved using perturbation and numerical schemes to show qualitatively similar responses for velocity and temperature. A streamline phenomenon is also considered.     

Mechanical Distension Induces Serotonin Release from Intestine as Revealed by Stretchable Electrochemical Sensing

The role of endogenous serotonin (5‐HT) in gastrointestinal motility is still highly controversial. Although electrochemical techniques allow for direct and real‐time recording of biomolecules, the dynamic monitoring of 5‐HT release from elastic and tubular intestine during motor reflexes remains a great challenge because of the specific peristalsis patterns and inevitable passivation of the sensing interface. A stretchable sensor with antifouling and decontamination properties was assembled from gold nanotubes, titanium dioxide nanoparticles, and carbon nanotubes. The sandwich‐like structure endowed the sensor with satisfying mechanical stability and electrochemical performance, high resistance against physical adsorption, and superior efficiency in the photodegradation of biofouling molecules. Insertion of the sensor into the lumen of rat ileum (the last section of the small intestine) successfully mimics intestinal peristalsis, and simultaneous real‐time monitoring of distension‐evoked 5‐HT release was possible for the first time. Our results unambiguously reveal that mechanical distension of the intestine induces endogenous 5‐HT overflow, and 5‐HT level is closely associated with the physiological or pathological states of the intestine.