Existence and nonexistence of curved front solution of a biological equation

This paper deals with the existence of curved front solution of a partial differential equation coming from a mathematical model of stroke. The equation is of reaction-diffusion type in a cylinder of radius R and of diffusion and absorption type outside of the cylinder. We prove the nonexistence of a travelling front when R is small enough and the existence if R is large enough using a recent energy method. We construct the travelling front as the limit in time of a solution with a well-chosen initial condition, in a travelling referential.     

Effects of Roxadustat on Erythropoietin Production in the Rat Body

Anemia is a major complication of chronic renal failure. To treat this anemia, prolylhydroxylase domain enzyme (PHD) inhibitors as well as erythropoiesis-stimulating agents (ESAs) have been used. Although PHD inhibitors rapidly stimulate erythropoietin (Epo) production, the precise sites of Epo production following the administration of these drugs have not been identified. We developed a novel method for the detection of the Epo protein that employs deglycosylation-coupled Western blotting. With protein deglycosylation, tissue Epo contents can be quantified over an extremely wide range. Using this method, we examined the effects of the PHD inhibitor, Roxadustat (ROX), and severe hypoxia on Epo production in various tissues in rats. We observed that ROX increased Epo mRNA expression in both the kidneys and liver. However, Epo protein was detected in the kidneys but not in the liver. Epo protein was also detected in the salivary glands, spleen, epididymis and ovaries. However, both PHD inhibitors (ROX) and severe hypoxia increased the Epo protein abundance only in the kidneys. These data show that, while Epo is produced in many tissues, PHD inhibitors as well as severe hypoxia regulate Epo production only in the kidneys.     

曲面相机阵列多分辨成像方法

针对现有成像系统因数据冗余而无法兼顾大视场、高分辨、高效性的问题,结合人眼视网膜变分辨成像和并列式复眼成像原理,设计一种多分辨率成像的复合仿生成像系统.该成像系统按照球面和平面兼顾的曲面布局方式,利用11个相机镜头构建相机阵列,组成了四个等级分辨率的子眼拍摄模块.通过物距100 m的远景实验和物距10 m的近景实验发现,该系统在实现高分辨成像的同时,获得总视场达150.8°×37.8°.多分辨率成像实验结果表明,该系统获取的图像的分辨率从中心视场到边缘视场逐渐降低,并且相较于中心清晰全视场成像,四级分辨率成像的拼接图像数据量减少了17.2倍的数据冗余.     

Performance of RNG Turbulence Modelling for Forced Convective Heat Transfer in Ducts

This investigation concerns numerical calculation of turbulent forced convective heat transfer and fluid flow in straight ducts using the RNG (Re-Normalized Group) turbulence method.

A computational method has been developed to predict the turbulent Reynolds stresses and turbulent heat fluxes in ducts with different turbulence models. The turbulent Reynolds stresses and other turbulent flow quantities are predicted with the RNG κ?ε model and the RNG non-linear κ-ε model of Speziale. The turbulent heat fluxes are modeled by the simple eddy diffusivity (SED) concept, GGDH and WET methods. Two wall functions are used, one for the velocity field and one for the temperature field. All the models arc implemented for an arbitrary three dimensional duct.

Fully developed condition is achieved by imposing cyclic boundary conditions in the main flow direction. The numerical approach is based on the finite volume technique with a non-staggered grid arrangement. The pressure-velocity coupling is handled by using the SIMPLEC-algorithm. The convective terms are treated by the QUICK, scheme while the diffusive terms are handled by the central-difference scheme. The hybrid scheme is used for solving the κ and ε equations.

The overall comparison between the models is presented in terms of friction factor and Nusselt number. The secondary flow generation is also of major concern.     

Anti-plane elastodynamic analysis of planes with multiple defects

The solution of a screw dislocation under time-harmonic condition is obtained in an infinite isotropic plane by means of the Fourier transform method. The stress components reveal the familiar Cauchy singularity at the location of dislocation. The solution is employed to derive integral equations for a plane weakened by cracks and cavities. Cavities are considered as closed curved cracks without singularity. Several examples are solved and the stress intensity factor of cracks and hoop stress on cavities are obtained.     

Two analytic methods applied to radiative transfer in the linear-anisotropic scattering medium with graded index and diffuse gray boundaries

The curved ray-tracing method is extended to radiative transfer in the graded index medium with diffuse gray boundary conditions instead of black boundary conditions and the pseudo-source adding method is extended to the case of the linear-anisotropic scattering medium with graded index from non-scattering medium. Furthermore, the equivalence of the two methods is verified by formulation derivation. As exact analytical solutions, both the methods have high accuracy and fast computational speed. The predicted temperature distributions and dimensionless radiative heat flux at radiative equilibrium are determined by the proposed methods, and the numerical results are compared with the data in references. The results show that the present methods have a good accuracy. Influences of various combinations of refractive index and boundary emissivities on the temperature distributions and dimensionless radiative heat flux are also investigated.     

Curved ray tracing method for one-dimensional radiative transfer in the linear-anisotropic scattering medium with graded index

The curved ray tracing method (CRT) is extended to radiative transfer in the linear-anisotropic scattering medium with graded index from non-scattering medium. In this paper, the CRT is presented to solve one-dimensional radiative transfer in the linear-anisotropic scattering gray medium with a linear refractive index and two black boundaries. The predicted temperature distributions and radiative heat flux at radiative equilibrium are determined by the proposed method, and numerical results are compared with the data in references. The results show that the CRT has a good accuracy for radiative transfer in the linear-anisotropic scattering medium with graded index and the dimensionless emissive power and dimensionless radiative heat flux depend on the dimensionless refractive index gradient. It can also be seen that the dimensionless refractive index gradient has important effects on the temperature discontinuity at the boundaries.     

扩展卡尔曼滤波和不敏卡尔曼滤波在实时雷达回波反演大气波导中的应用

为了改善雷达回波反演大气波导(RFC)方面存在的单时次、单方位角反演的问题,提出利用扩展卡尔曼滤波和不敏卡尔曼滤波的反演算法对大气波导结构的多方位角实时跟踪反演. 在卡尔曼滤波方法中分别给出大气波导结构的参数化方程、观测方程、滤波算法的状态转移方程,最后导出滤波反演算法的迭代求解流程. 在大气波导结构不随时间变化和随时间变化的两种条件下,对扩展卡尔曼滤波和不敏卡尔曼滤波算法进行数值实验. 实验结果表明,不敏卡尔曼滤波更适用于RFC这高度非线性反演问题,它可能今后为大气波导结构多方位角实时跟踪反演的业务化运行提供理论基础与技术保证. 关键词： 大气波导 雷达回波 扩展卡尔曼滤波 不敏卡尔曼滤波