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排序方式: 共有407条查询结果,搜索用时 31 毫秒
1.
Physical activity and risedronate sodium have effects on metabolic bone diseases, maintaining the integrity of bone tissue. Our objective was to evaluate the effects of swimming associated with risedronate as a prophylactic means in osteopenic bone of ovariectomized rats. A total of 24 animals of the Wistar strain were used and separated into four groups containing six animals: Ovariectomy (OVX), ovariectomy and swimming (OVXS), ovariectomy and risedronate (OVXM), ovariectomy, risedronate and swimming (OVXMS). The effectiveness of the treatments were evaluated using the tibia by means of biomechanical, radiographic, histomorphometric analyzes. Statistical analysis was performed by the non-parametric Kruskal–Wallis test (p < 0.05). The OVXM and OVXMS groups showed higher values compared to OVX in maximum strength and rigidity. Microscopic analysis showed increased trabecular bone in the OVXM group in relation to the others, and in the OVXMS compared to OVXS. Proximal densitometry in the OVXM and OVXMS groups showed higher values than the OVX and OVXS groups. There were no significant differences in overall densitometry. In conclusion, when comparing the prophylactic means, risedronate was able to preserve bone mass significantly, unlike exercise where an improvement of bone tissue was observed, although not significant, and when swimming and risedronate are combined the result was even better. 相似文献
2.
Chris Quigg 《EPJ direct》2002,4(1):1-15
We study the branching ratio, CP-violating asymmetry, forward-backward asymmetry and the CP-violating asymmetry in the forward-backward asymmetry for the exclusive decay B → Kτ+τ− in the two Higgs doublet model with tree level flavor changing neutral currents (model III). We analyse the dependencies of these quantities on the neutral Higgs boson contributions and the CP parameter sinθ in the model III. We observe that to determine the neutral Higgs boson effects, the measurements of the forward-backward asymmetry and the CP-violating asymmetry in the forward-backward asymmetry for the decay B → Kτ+τ− are promising. 相似文献
3.
胡斌 《广东微量元素科学》1997,4(9):51-55
儿童缺锌是较普遍的社会现象,济南泉城微量元素生命研究所研制的复合蛋白锌系采用生物技术转化而得到的一种蛋白复合物,属生物合成的有机微量元素,经急性和长期毒性试验均未发现毒副作用,经检测不含兴奋剂,用于临床后,对纠正偏食厌食,反复呼吸道感染和智力低下等近千例儿童疾患,显示了可喜的临床效果,证明是优质有机补锌剂。 相似文献
4.
E. Marklová 《Chromatographia》1997,45(1):195-198
Summary Thin-layer chromatography (TLC) is a rapid, reliable and inexpensive screening technique for diagnosis of inherited metabolic
diseases (IMD). Our screening program encompasses five main situations where the use of TLC is considered to be vindicated:
(i) analysis of amino acids; (ii) screening for sugar defects; (iii) detection of pathological oligosaccharidurias; (iv) screening
for organic acid disorders; and (v) detection of abnormalities in tryptophan metabolism. Examples are presented of chromatograms
obtained from pathological samples.
Presented at the 21st ISC held in Stuttgart, Germany, 15th–20th September, 1996 相似文献
5.
微量元素与防病治病 总被引:8,自引:3,他引:8
宫振沛 《广东微量元素科学》2002,9(12):54-61
介绍了微量元素在防治疾病中的作用及对健康长寿的意义,涉及人体必需微量元素,有害元素,有机锗,微量元素是健康长寿的重要手段以及微量元素与现代文明病。 相似文献
6.
Boris Pejin Kristina Tešanović Dragica Jakovljević Sonja Kaišarević Filip Šibul Milena Rašeta 《Natural product research》2019,33(5):750-754
The polysaccharide (PSH) extracts from the edible mushroom species Coprinus comatus and Coprinellus truncorum were screened in liquid for their acetylcholinesterase inhibitory (AChE) activity. Both extracts were found to display inhibition of the aforementioned enzyme reaching similar IC50 values of 0.62 ± 0.07 and 0.61 ± 0.03 mg/mL, respectively. According to the means of FTIR spectroscopy, these PSH extracts mostly contained β-glucans. However, the presence of some proteins and polyphenolics as minor ingredients were also detected. Compared with existing literature data for anti-AChE activity of the sugar samples, the findings within this study may be treated as a profound bioactivity. Consequently, this study puts some light on the possible use of the screened macrofungi in the palliative treatment of Alzheimer’s disease. 相似文献
7.
Bolis Basit Hans Gü nzler 《Transactions of the American Mathematical Society》1996,348(11):4489-4500
Let be a semigroup and a topological space. Let be an Abelian topological group. The right differences of a function are defined by for . Let be continuous at the identity of for all in a neighbourhood of . We give conditions on or range under which is continuous for any topological space . We also seek conditions on under which we conclude that is continuous at for arbitrary . This led us to introduce new classes of semigroups containing all complete metric and locally countably compact quasitopological groups. In this paper we study these classes and explore their relation with Namioka spaces.
8.
Circular high-performance thin-layer chromatography (HPTLC) has been used to differentiate a series of twelve tricyclic neuroleptics, using both normal phase and reverse phase procedures. The use of normal phase systems also allows the resolution of geometric isomers of chlorprothixene, clopenthixol and flupenthixol. Thirteen sulphonamides and Trirnethoprim may also be distinguished using HPTLC. 相似文献
9.
金属蛋白研究中几个值得注意的动向 总被引:5,自引:0,他引:5
本文叙述了金属蛋白和金属酶研究中近年来几个值得注意的发展动向,即与金属离子相关的疾病(特别是神经退行性疾病)、金属离子在蛋白质的折叠、聚集和装配中的作用,金属伴侣分子、金属蛋白的设计和构建、金属蛋白与DNA相互作用。 相似文献
10.
Kozyr AV Kolesnikov AV Aleksandrova ES Sashchenko LP Gnuchev NV Favorov PV Kotelnikov MA Iakhnina EI Astsaturov IA Prokaeva TB Alekberova ZS Suchkov SV Gabibov AG 《Applied biochemistry and biotechnology》1998,75(1):45-61
DNA-hydrolyzing activity of IgG autoantibodies from sera of patients with various types of lymphoproliferative diseases was
investigated. The association of DNA-hydrolyzing activity with the antibody (Ab) fraction has been proved by newly developed
affinity-capture assay. Study of abzyme incidence in blood tumors and systemic lupus erythematosis (SLE) revealed linkage
of anti-DNA Ab catalysts to mature B-cell tumors, and increased probability of DNA-abzymes formation on the background of
autoimmune manifestations. These data suggest possible similarity between mechanisms of abzyme formation in SLE and B-cell
lymphomas. A new mechanism of formation of DNA-specific catalytic Abs has been proposed based on the increased crossreactivity
of polyclonal DNA-abzymes to DNA-depleted nuclear matrix proteins. The possibility of the abzyme production as Ab to the energetically
destabilized ground state of the antigen has been discussed. Preliminary results were obtained that indicate the complement-independent
cytotoxicity of anti-DNA autoantibodies isolated from blood of patients with SLE and chronic lymphocytic leukemia. 相似文献