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Immacolata Tufano Maria Rosaria Iesce Elisabetta Buommino Flavio Cermola 《Natural product research》2020,34(15):2109-2115
AbstractFurolignan-type natural products, possessing important biological properties, have been synthesized from a commercially available furan. The elaborated synthetic strategy is based on an innovative Friedel-Crafts reaction starting from an alcohol or a carboxylic acid and triflic anhydride as promoter. Through this synthetic strategy, furolignans having two different aryl groups have been obtained. The products have been evaluated for their antimicrobial properties on Gram positive and Gram negative bacteria, in order to compare their biological activities with those of natural analogues. 相似文献
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