Synthese und Geruch von (Z)-Dehydro-homo-β-santalol

Summary Guided by molecular modeling studies, the synthesis of the title compound is described. The organoleptic evaluation proved the predicted real sandal like odour of (Z)-dehydro-homo--santalol.

Aus den Diplomarbeiten von C.P. (1991), I.P. und B.Ö. (1992), Universität Wien     

芳香PET树脂母粒的研制

通过丙烯酸和丙烯酸正丁酯溶液共聚合，得到丙烯酸－丙烯酸正丁酯共聚物，该树脂与环氧氯丙烷反应后再与PET树脂切片继续反应，可使PET树脂切片表面形成聚丙烯酸酯自膨润型吸油网络结构，将表面具有聚丙烯酸酯自身膨润型吸油网络结构的PET树脂切片（简称为留香剂）在油溶性香精中浸泡，香精就被吸附在留香剂表面，即得到芳香PET树脂母粒。用SEM观察了母粒的表面结构形态。     

气相色谱–质谱法快速分析化妆品中3种香精香料

建立气相色谱-质谱法快速测定化妆品中甲基柏木酮、甲基柏木醚、壬酸3种香精香料的方法。样品用甲醇超声提取,经高速冷冻离心,上清液干燥脱水后经0.45 μm滤膜过滤,直接注入气相色谱-质谱仪进行测定,用选择离子和保留时间定性,外标法定量。甲基柏木酮、甲基柏木醚、壬酸在各自的质量浓度范围内与色谱峰面积成良好的线性关系,相关系数分别为0.9992,0.9991,0.9994,检出限分别为0.05,0.1,0.1 mg/kg。测定结果的相对标准偏差为2.1%~6.6%(n=5),样品加标回收率为91.5%~97.7%。该方法准确度和灵敏度高,样品用量少,前处理简单,可同时测定化妆品中3种香精香料。     

Cationic and temperature-sensitive liposomes loaded with eugenol for the application to silk

Silk has been widely used in the clothing industry due to their soft and smooth features, good biocompatibility, good heat dissipation, warmth and ultraviolet resistance. The application of fragrance to silk can significantly improve the performance of silk. However, there are two key scientific problems that need to be solved: slowing down the release rate of fragrances and increasing the scent lasting time of silk. In this study, cationic and temperature-sensitive liposomes were designed and prepared to encapsulate eugenol. These fragrance-loaded liposomes significantly slowed down the release rate of the fragrance and controlled the release rate of the fragrance in a thermo-sensitive manner. The liposomes adhered to the silk through electrostatic adsorption interaction. The positive charge on the fragrance-loaded liposomes neutralized much negative charge on silk and thereby increasing the adhesion efficiency.     

多组分烟用香精定量分析方法的研究进展

综述了近年来烟用香精、香料各组分化合物的定量分析方法的研究进展。面积归一化法、内标法、外标法和标准加入法等常用色谱定量分析方法主要用于烟用香精、香料中目标化合物或单个组分的测定;多标定量法、特征峰-内标定量法和多元校正法能深入剖析烟用香精复杂体系中各组分含量(引用文献48篇)。     

Relative effectiveness of pretreatments on performance of Rhizomucor miehei lipase in nonpolar reaction media

Enzymes can be used in nonpolar reaction media to modify waterinsoluble substrates. A variety of pretreatments, applied to the enzyme prior to introduction to the nonpolar media, can improve enzyme activity. However, the various pretreatments have not been studied using directly comparable conditions, nor have they been applied simultaneously to test for interactive effects. This work evaluates pretreatment of lipase with various classes of additives. The pretreated lipase is used to catalyze esterification between citronellol and acetic acid in a medium of n-hexane. The effectiveness of a particular pretreatment is presented in terms of relative performance (RP), which is equal to the number of times faster the pretreated lipase catalyzes the reaction relative to untreated lipase. The individual and interactive effects of the pretreatment factors were studied and compared. Buffer salts had a much stronger performance-enhancing effect than nonbuffer salts; pretreatment with 90% (w/w) sodium phosphate yielded lipase with an RP of approx 64. A strong interaction was found between the treatments with sodium phosphate and pH adjustment. These treatments may mitigate the inhibitory effect of acetic acid. Activating effects of phase interfaces and active-site protectants are shown to be complementary to other treatments, demonstrating that they likely act by distinct mechanisms.     

Carrageenan for encapsulation and immobilization of flavor,fragrance, probiotics,and enzymes: A review

Carrageenans are sulfated polysaccharides obtained from sea weed. There are six types of carrageenans. They have been explored as gelling agents, control release vehicles, and encapsulating agents. It has been established that carrageenans, in the form of gels, beads and films, can efficiently encapsulate flavors, fragrances, probiotics, and enzymes. Flavors and fragrances are encapsulated to reduce their volatility. Probiotic encapsulation results in enhanced stability. Immobilization of enzymes in carrageenans improves their biocatalytic performance and stability. This review has summarized how carrageenans have been extensively investigated as potential encapsulating agents for the above-mentioned attributes.     

高效液相色谱-串联质谱法检测玩具中5种香豆素类致敏性香味剂

建立了一种简单、快速、准确测定玩具中香豆素、7-甲氧基香豆素、二氢香豆素、7-甲基香豆素、7-乙氧基-4-甲基香豆素5种香豆素类致敏性香味剂的检测方法。样品经四氢呋喃超声提取,提取液浓缩至近干,以25 mL甲醇 溶解残渣定容后进行高效液相色谱-串联质谱分析。色谱流动相为乙腈和0.1%乙酸水溶液,梯度洗脱,多反应监 测（MRM）模式进行定性和定量分析。5种目标物的工作曲线线性范围均为10～1 000 μg/L;除了二氢香豆素的定 量限（信噪比（S/N）>10）为5.0 μg/L外,其他化合物均为2.0 μg/L;在3种不同类型的样品中添加高、中、低水平的5种目标物标准品,其加标回收率为93.2%～105.8%,相对标准偏差为3.65%～8.27%。应用本方法对12种玩具和儿童用品样品进行了测试,其中9个样品中检出了香豆素类致敏性香味剂,有两个样品中香豆素和7-甲氧基香豆素的含量超过了欧盟玩具新指令的限量要求。     

Surface comparisons of some odour molecules: Conformational calculations on sandalwood odour V

Summary Molecular surface comparison seems to be a very suitable tool for the investigation of small differences between biologically active and inactive compounds of the same structural type. A fast method for such comparisons, based on volume matching followed by the estimation of comparable surface dots, is presented and applied on a few selected sandalwood odour molecules.     

A rapid method for molecular shape comparison of medium-sized molecules. Conformational calculations on sandalwood odor,IV

Summary A fast method of a surface comparison of two or more molecules to be matched is presented. The Van der Waals surfaces of molecules are described by points calculated as the intersection of grid lines with the molecular surface. The mean surface of various molecules with the same biological activity can be constructed. It is used for further comparisons with similar molecules lacking this activity. Deviations of any molecular surface from the mean surface can be mapped onto the surface. The method was tested on a distinct group of sandalwood odor molecules and it was shown that such matching and comparison procedures are useful in the investigation of odor structure-activity relationships proposed as CAFD (computer aided fragrance design).Dedicated to Prof. Dr. W. Fleischhacker, on occasion of his 60th anniversary