Copper(II)‐Catalyzed Tandem Synthesis of Substituted 3‐Methyleneisoindolin‐1‐ones

An efficient strategy for the synthesis of a variety of 3‐methyleneisoindolin‐1‐ones has been developed. The reaction proceeded from coupling of 2‐iodobenzamides (or 2‐bromobenzamides) and terminal alkynes via Cu(OAc)₂·H₂O/2,2′‐biimidazole catalyzed in DMF at 60°C and subsequent additive cyclization produced substituted 3‐methyleneisoindolin‐1‐ones in good to excellent yields.     

基于5-磺基水杨酸的单、双核铜(Ⅱ)三元混配配合物的合成及晶体结构

以5-磺基水杨酸和咪唑衍生物为配体合成了单核、双核结构的三元混配Cu(Ⅱ)配合物:[Cu(H2 biim)(Hssal)(H2O)2]·H2O(1)和{[Cu(MeHbiim)(Hssal)(H2O)]·0.5H2O}2(2)(H3ssal=5-磺基水杨酸,H2biim=2,2'-联咪唑,MeHbiim=N-甲基-2,...     

Synthesis,Crystal Structure,and DNA‐Binding Properties of a New Cd(II) Complex Involving 2‐(2‐1H‐Imidazolyl)‐1H‐Imdazolium Ligand

A new Cd(II) complex of Cd(H₃biim)₂(NCS)₂Cl₂ [H₃biim=2‐(2‐1H‐imidazolyl)‐1H‐imidazolium] was synthesized and characterized by elemental analyses, FT‐IR and X‐ray single crystal diffraction. In the X‐ray crystallography structure, the cadmium(II) ion is coordinated by two nitrogen atoms of two 2‐(2‐1H‐imidazolyl)‐ 1H‐imdazolium, two nitrogen atoms of two thiocyanate ions and two Cl^?. The interaction of the complex with calf thymus DNA was investigated through electronic absorption spectroscopy, fluorescence spectroscopy, viscosity measurement, cyclic voltammetry and gel electrophoresis. These results show that the Cd(II) complex can electrostatically bind to the phosphate group of DNA backbone. Interestingly, we found that the complex can cleave the pBR322 DNA at pH=7.2 and 37°C.     

Copper(Ⅱ)and 1,1 '-Trimethylene-2,2'-biimidazole-promoted Arylation of Acetylacetone with Aryl Iodides

A new and efficient way was developed to carry out the reaction of acetylacetone with aryl iodides under the assistance of Cu(II) and 1,1′‐trimethylene‐2,2′‐biimidazole at 100°C. 3‐Aryl‐2,4‐pentanediones were obtained in excellent yields.     

锰(Ⅱ)配合物修饰的Preyssler型多金属氧酸盐的合成、晶体结构和催化性能

利用水热法合成了一个新的Mn（Ⅱ）-H₂biim/H₂O配合物修饰的Preyssler型多金属氧酸盐,{[Mn（H₂biim）₂（H₂O）₂]₂[Mn（H₂biim）₃]₅Cl}[H（NaP₅W₃₀O₁₁₀）]·20H₂O（1）（H₂biim=2,2’-联咪唑）,并通过单晶X-射线衍射、元素分析、IR光谱分析、热重分析和电化学分析等对其进行了表征,同时探讨了合成环己酮乙二醇缩酮的催化活性。结构分析表明,化合物1分子中含有1个[NaP₅W₃₀O₁₁₀]^14-多阴离子,其周围有7个游离的Mn（Ⅱ）-H₂biim/H₂O配合物单元,分子间通过N-H…O/OW和N-H…Cl两种类型的氢键构成三维网络结构。研究表明该化合物是1种可重复使用、性能良好、环境友好型羰基保护催化剂。     

对苯二甲酸及双酚A衍生物构筑的二维镉配位聚合物的合成、结构及性质

以4,4-二（4-羟乙基苯并咪唑基苯基）丙烷（L₁）,4,4-二（4-羟乙基咪唑基苯基）丙烷（L₂）为原料,通过水热法得到2个二维结构的配位聚合物{[Cd（L₁）（bdc）H₂O]·2DMA}_n（1）,[Cd（L₂）（bdc）H₂O]_n（2）（H₂bdc=对苯二甲酸,DMA=N,N-二甲基乙酰胺）,通过X-射线单晶洐射、热重以及红外光谱对其进行了表征。结果显示晶体1为单斜晶系,P2/c空间群。晶体2为单斜晶系,C2/c空间群。配合物2为2D→2D穿插结构。热重分析表明配合物1和2分别在343和325℃时分解。     

Syntheses and Crystal Structures of a Cadmium(Ⅱ) and a Zinc(Ⅱ) Complexes with the Flexible Ligand 1-Acetic Acid-2, 2'-biimidazole

Reactions of NaAcebiim(NaAcebiim = 1-acetic acid-2, 2′-biimidazole monosodium salt) and cadmium or zinc nitrate produce two supramolecular architectures, namely, 1D [Cd(Acebiim)(NO3)(H2O)]n(1) and 0D [Zn(Acebiim)2(H2O)2]·2H2O(2) in acidic aqueous solutions. Single-crystal X-ray diffraction analysis reveals that complex 1 crystallizes in the triclinic system, space group P1, and 2 is of monoclinic system, space group P21/n. In 1, two nitrate groups link two Cd(Ⅱ) ions forming [Cd2(NO3)2(H2O)2] as secondary building units that are interconnected by the Acebiim- ligand into an infinite ladder. In 2, the hydrogen-bonded synthon R22(16) between the N–H moieties and carboxylic acid link [Zn(Acebiim)2(H2O)2], generating a 1D-extended ribbon. Moreover, hydrogen bonds and π-π interactions further stabilize the 3D supramolecular architecture.     

Efficient CS Cross‐Coupling of Thiols with Aryl Iodides Catalyzed by Cu(OAc)2·H2O and 2,2′‐Biimidazole

The classical Ullmann C? S cross coupling reaction of aryl iodides with aromatic/alkyl thiols under catalysis of 15 mol% Cu(OAc)₂·H₂O and 15 mol% 2,2′‐biimidazole works at 80°C in DMSO for 3 h to provide a variety of aryl sulfides in good to excellent yields.     

2,2’-二(1,1’-4-甲基-吡啶)联咪唑和芳香族羧酸为配体构筑的配位聚合物的水热合成、结构及性质研究

2,2’-二(1,1’-4-甲基-吡啶)联咪唑(L)、芳香二羧酸与乙酸镉在水热条件下反应得到了配位聚合物[Cd2(L)(p-bdc)2(H2O)2]n(1)和[Cd(L)0.5(m-bdc)]n(2),并用单晶衍射仪定义了其晶体结构.结构分析表明,配合物1结晶属于正交晶系,Ibca空间群,配合物2结晶属于单斜晶系,C2/c空间群,进一步分析表明,所合成的2个化合物都是有扭曲α-Po拓扑的三维网络结构.在室温条件下,配体L和2个配合物均表现出较好的荧光性质.     

有机膦功能化联咪唑的合成与表征

从N,N’-二烷基酯联咪唑出发,经过还原、氯代、亲核取代反应,合成了N,N’-二烷基膦联咪唑.产物经过了红外、核磁共振及质谱表征.反应前体N,N’-二醇联咪唑和N,N’-二烷基氯联咪唑可作为起始物,合成得到一系列联咪唑衍生物.