排序方式: 共有57条查询结果,搜索用时 31 毫秒
1.
5,6-Bis(dimethylamino)acenaphthylene is readily involved in [4+2] cycloaddition reactions with symm-tetrazine derivatives to form new proton sponges with the diazafluoranthene skeleton. Under analogous condition, 1,8-bis(dimethylamino)-4-vinylnaphthalene gave 4-pyridazinyl derivatives. The relative reactivities of 5,6-bis(dimethylamino)acenaphthylene, 1,8-bis(dimethylamino)-4-vinylnaphthalene, 5-dimethylaminoacenaphthylene, and acenaphthylene in the reactions with 3,6-diphenyl-symm-tetrazine are in a ratio of 32 : 17 : 14 : 1. The site of protonation of 3,4-bis(dimethylamino)-7,10-diphenyl-8,9-diazafluoranthene is controlled by the basicity of the solvent. The reaction in acetonitrile afforded the cation stabilized by an intramolecular hydrogen bond, whereas the reaction in dimethyl sulfoxide gave rise to the resonance-stabilized cation. 6,7-Bis(dimethylamino)phenalen-1-one was protonated only at the carbonyl group. 相似文献
2.
S.D ShaposhnikovS.V Pirogov S.F Mel'nikova I.V TselinskyC Näther T GraeningT Traulsen W Friedrichsen 《Tetrahedron》2003,59(7):1059-1066
Interaction of 3,4-diacylfuroxans with hydroxylamine hydrochloride results in the formation of substituted 4,5-bis (hydroximino)-4,5-dihydroisoxazoles, whereas the reaction of 3,4-bis(4-methylfurazanoyl-3)furoxan with hydrazine hydrate in acetic acid affords 3-[4,5-bis(hydroximino)-4,5-dihydro-1H-pyrazol-3-yl]-4-methylfurazan. N-Acyl-, N-nitro-, N-alkyl- and N-adamantyl derivatives of the latter compound have been synthesized. X-Ray structure determinations together with density functional theoretical calculations are reported. 相似文献
3.
J. M. Quintela M. C. Veiga R. Alvarez-Sarandés L. González C. Peinador 《Monatshefte für Chemie / Chemical Monthly》1996,127(10):1037-1043
Summary 8,9-Diphenylpyridazino[4,3:4,5]thieno[3,2-d]-1,2,3-triazin-4(3H)-one (2), 3-substituted 8,9-diphenylpyridazino[4,3:4,5]thieno[3,2-d]-1,2,3-triazin-4(3H)-ones (3a–c), 3,4-diphenylpyrimido[4,5:4,5]thieno[2,3-c]pyridazin-8(7H)-one (4), 8-chloro-3,4-diphenylpyrimido[4,5:4,5]thieno[2,3-c]pyridazine (5), 8-substituted 3,4-diphenylpyrimido[4,5:4,5]thieno[2,3-c]pyridazines (6a–h) and 7-substituted 3,4-diphenylpyrimido[4,5:4,5]thieno[2,3-c]pyridazin-8(7H)-ones(7a–c) were synthesized from 5-amino-3,4-diphenylthieno[2,3-c]pyridazine-6-carboxamide (1).
Synthese neuer Pyridazino[4,3:4,5]thieno[3,2-d]-1,2,3-triazin-und Pyrimido[4,5:4,5]thieno[2,3-c]pyridazin-Derivate
Zusammenfassung Folgende Verbindungen wurden ausgehend von 5-Amino-3,4-diphenylthieno[2,3-c]pyridazin-6-carboxamid (1) synthetisiert: 8,9-Diphenylpyridazino[4,3:4,5]thieno[3,2-d]-1,2,3-triazin-4(3H)-on (2), 3-substituierte 8,9-Diphenylpyridazino[4,3:4,5]thieno[3,2-d]-1,2,3-triazin-4(3H)-one (3a–c), 3,4-Diphenylpyrimido[4,5:4,5]thieno[2,3-c]pyridazin-8[7H]-on (4), 8-Chlor-3,4-diphenylpyrimido[4,5:4,5]thieno[2,3-c]pyridazin (5), 8-substituierte 3,4-Diphenylpyrimido[4,5:4,5]thieno[2,3-c]pyridazine (6a–h) und 7-substituierte 3,4-Diphenylpyrimido[4,5:4,5]thieno[2,3-c]pyridazin-8(7H)-one (7a–c).相似文献
4.
Carbonyl compounds reacted with stable phosphonium ylides in D2O to give α-deuterated-α,β-unsaturated carbonyl compounds in the same flask. The chemical yield and deuterium incorporation are excellent under our procedure. The fragile group like ozonide was compatible with our reaction condition. 相似文献
5.
Saleh Al-Mousawi Abdel-Zaher Elassar Morsy Ahmed El-Apasery 《Phosphorus, sulfur, and silicon and the related elements》2013,188(8):1755-1771
Heating diazoaminobenzene with active methylene compounds 1–3 in microwave oven in acetic acid, in the presence of hydrochloric acid, afforded the corresponding arylhydrazones 5–7. These reaction products were condensed with ethyl cyanoacetate in a domestic microwave oven after 1–2 minutes heating to yield the pyridazinones 8–12. Compounds 8c and 12 reacted with sulfur in basic DMF solution, in microwave oven using MORE technology to yield the thienopyridazinone 14 and 16 respectively. While 17 was produced when 8b was treated like wise with sulfur and DMF in the presence of piperidine. Compounds 16 coupled with aromatic diazonium salts to yield arylazo derivatives 21a–c. 相似文献
6.
An efficient two‐step synthesis of 3,6‐diaminopyridazine from 3,6‐dichloropyridazine is reported. In this synthetic procedure, 4‐methoxybenzylamine was used as a nitrogen source to substitute the chloro groups of 3,6‐dichloropyridazine to form N,N′‐bis‐(4‐methoxybenzyl)‐pyridazine‐3,6‐diamine. The 4‐methoxybenzyl groups were then removed by treatment with hydrochloric acid to provide the target 3,6‐diaminopyridazine with an overall yield of 78%. 相似文献
7.
A number of 4,5‐dichloro‐ and 4,5‐dibromopyridazin‐3‐ones and ‐3,6‐diones with polyfluoro substituents at position 2 were obtained in good yields by microwave‐assisted method. The oxopyridazines as well as their respective 5‐dimethylaminoethylamino derivatives were tested for antibacterial, antiviral, and antiprotozoal activity. 相似文献
8.
Sebastian Hamer Jan-Simon von Glasenapp Fynn Röhricht Dr. Chao Li Prof. Dr. Richard Berndt Prof. Dr. Rainer Herges 《Chemistry (Weinheim an der Bergstrasse, Germany)》2021,27(69):17452-17458
A set of dipolar molecular rotor compounds was designed, synthesized and adsorbed as self-assembled 2D arrays on Ag(111) surfaces. The title molecules are constructed from three building blocks: (a) 4,8,12-trioxatriangulene (TOTA) platforms that are known to physisorb on metal surfaces such as Au(111) and Ag(111), (b) phenyl groups attached to the central carbon atom that function as pivot joints to reduce the barrier to rotation, (c) pyridine and pyridazine units as small dipolar units on top. Theoretical calculations and scanning tunneling microscopy (STM) investigations hint at the fact that the dipoles of neighboring rotors interact through space through pairs of energetically favorable head-to-tail arrangements. 相似文献
9.
Hans Junek Manfred Klade Heinz Sterk 《Monatshefte für Chemie / Chemical Monthly》1989,120(8-9):781-788
Summary 1-Dicyanomethylene-3-indanone (1) shows a remarkable reactivity of the carbonyl- and the methylene-function towards nucleophiles. With anilines and phenylhydrazine, resp., the deep-red colored pentamethinecyanines2 and3 are formed, azocoupling leads to indano-pyridazines4. With diphenylformamidines anilinomethylene-indanones5 are obtained in a primary reaction, followed by ring closure and Dimroth-rearrangement to indano-pyridines6.13C- and15N-NMR-spectrocopy is used for confirmation of the structures.
Herrn Prof. Dr. J. Schurz zum 65. Geburtstag gewidmet 相似文献
10.