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Certain 17β-aminoderivatives of 5α-steroids based on tigogenin were synthesized and their antitumor activity was studied. The structures of the synthesized compounds were confirmed by NMR and IR spectroscopy and mass spectrometry. __________ Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 263–265, May–June, 2006.  相似文献   
2.
17α-Amino-5ga-androst-2-ene was synthesized from epiandrosterone via formation of the tosylate followed by nucleophilic substitution by azide and reduction with LiAlH4. The structures of the products were proved by NMR and IR spectroscopy and mass spectrometry. __________ Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 257–258, May–June, 2006.  相似文献   
3.
A new method for synthesizing 17-amino-5-androstane was developed based on tigogenin. The configuration at C-17 was proved by PMR.  相似文献   
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