全文获取类型
收费全文 | 486篇 |
免费 | 19篇 |
国内免费 | 68篇 |
专业分类
化学 | 566篇 |
综合类 | 3篇 |
物理学 | 4篇 |
出版年
2023年 | 2篇 |
2022年 | 2篇 |
2021年 | 5篇 |
2020年 | 5篇 |
2019年 | 11篇 |
2018年 | 14篇 |
2017年 | 12篇 |
2016年 | 12篇 |
2015年 | 6篇 |
2014年 | 15篇 |
2013年 | 101篇 |
2012年 | 26篇 |
2011年 | 34篇 |
2010年 | 20篇 |
2009年 | 27篇 |
2008年 | 23篇 |
2007年 | 26篇 |
2006年 | 37篇 |
2005年 | 27篇 |
2004年 | 29篇 |
2003年 | 43篇 |
2002年 | 12篇 |
2001年 | 12篇 |
2000年 | 10篇 |
1999年 | 8篇 |
1998年 | 4篇 |
1997年 | 7篇 |
1996年 | 4篇 |
1995年 | 6篇 |
1994年 | 1篇 |
1993年 | 7篇 |
1992年 | 2篇 |
1991年 | 2篇 |
1990年 | 5篇 |
1989年 | 2篇 |
1988年 | 4篇 |
1987年 | 1篇 |
1986年 | 2篇 |
1985年 | 1篇 |
1984年 | 3篇 |
1979年 | 1篇 |
1977年 | 1篇 |
1970年 | 1篇 |
排序方式: 共有573条查询结果,搜索用时 15 毫秒
1.
A short and highly efficient approach was applied for the total synthesis of the gypsy moth sex pheromone (+)-disparlure and its enantiomer from isopropylidene D- and L-erythrose, using a common strategy. 相似文献
2.
Hirofumi Kuroda Emi Hanaki Hironori Izawa Michiko Kano Hiromi Itahashi 《Tetrahedron》2004,60(8):1913-1920
α-Vinylfurans were obtained by phosphine-initiated cyclization of various enynes bearing a carbonyl group at the ene end in the presence of various aldehydes, in moderate to high yields. The reaction may consist of 1,6-addition of phosphine to the enynes, ring closure, and Wittig reaction between the ylid resulting from cyclization and an aldehyde. Thus, various aldehydes were able to be used in the reaction. The reaction was influenced greatly by the substituents at the acetylene position (R1) and the α-position of the carbonyl group (R3). 相似文献
3.
Introduction Polysubstituted arenes are important intermediates in synthetic medicines and dyestuffs, and the fluorinated analogues are more attractive as a result of their lipo-philicity and the increment of activity.1,2 Therefore, to study the convenient and efficient synthesis of polysub-stituted arenes is valuable in organic synthetic method-ology. We have designed a simple synthesis of fluori-nated polysubstituted arenes through the intramolecular Wittig reaction of a new phosphorous ylid… 相似文献
4.
5.
Syntheses of Two Potential Ligands for Tc-99m Labeling as Diagnosis Agents of Alzheimer''''s Disease
Two types of ligands-biphenyl and stilbene derivatives, whichcan be labeled with Tc-99m for the diagnosis of Alzheimer'sdisease (AD) have been synthesized successfully. The key stepsin these two syntheses involved Suzuki reaction and Wittig reac-tion respectively. The new discovered debromination reactionmay be expanded to the compounds with double or triple bondadjacent to the carbon atom bearing the bromine atoms. Thesetypes of syntheses provide a route to a series of biphenyl andstilbene derivatives that will benefit the search of new imagingagents for AD. 相似文献
6.
A total synthesis of d-(+)-biotin is described starting from d-(+)-glucosamine using acyliminium chemistry. 相似文献
7.
Mukund K. Gurjar Seetaram Mohapatra Usha D. Phalgune Vedavati G. Puranik Debendra K. Mohapatra 《Tetrahedron letters》2004,45(42):7899-7902
An enantioselective synthesis of the C12-C29 fragment of amphidinolide E is described. Key transformations include an intramolecular mercuriocyclization reaction, stereoselective introduction of methyl group at the C2 position, and Stille coupling for the introduction of the diene side chain. 相似文献
8.
Kate N. Fanning 《Tetrahedron letters》2007,48(48):8479-8481
A simple and direct approach for the synthesis of (S)-gizzerosine, an amino acid responsible for the disease, black vomit, and a potent histamine H2-receptor, has been developed in 10 steps and in 31% overall yield from l-aspartic acid. The key steps involved a two-carbon homologation of an l-aspartic acid semi-aldehyde and direct alkylation of unprotected histamine with a 6-hydroxynorleucine derivative. 相似文献
9.
The regio- and stereoselectivity of the reactions of carbanions, generated from alkanals, carboxylates of the type XYCHCOOEt (X = EtOOC, CN, Ac; Y = H, Br), or derivatives of 3-methyl-4-phosphono-2-butenoic acid using PTC techniques, with aldehydes of various types (alkanals, ,-enals, cross-conjugated enedials, benzaldehydes,etc.) are reviewed. The factors affecting the outcome of these reactions are discussed. The carbanion analogs, triphenylphosphorus ylides, are shown to attack selectively at one of the aldehyde groups of aromatic dialdehydes. The regularities found for the title reactions were used in the syntheses of some biologically active isoprenoids.Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 10, pp. 1867–1885, October, 1995. 相似文献
10.
Phosphonium or arsonium salt 1 can undergo the tandem reaction of deprotonation -oxidation-Wittig reaction with alcohol 2 in the presence of sodium hydroxide and manganese dioxide,which affords a general simplified method for the stereoselective synthesis of (E)- α-β-unsaturated esters 3. 相似文献