Author Index Vol.32,Nos.1-12,2014

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彝药双参主须根有效成分FTIR分析

双参是一味彝医特色用药。本文获取了双参主根和须根的红外特征谱,发现二者相差较大。分析表明主根和须根所含主要成分不同,主根含淀粉较多,须根含纤维素较多。文章还分析了双参的IR图谱和有效成分(即药物活性)之间的关系。实验结果表明,主根和须根的药物活性也不完全相同。在两者的图谱中在1373cm-1和1245cm-1处都有峰,表明主根、须根都有活血化瘀的功能;此外主根在931cm-1处有峰,有保肝的活性;须根却在894cm-1,832cm-1处有峰,表示须根有抗肝炎作用,最后在须根中还含有生物碱(在1736部分cm-1处有小峰),说明它还有杀菌解毒功能。本文对双参的主根和须根的不同药效提供了分子依据,对彝药的有效成分与IR图谱的联系作出了首次初步探索。     

A target and nontarget strategy for identification or characterization of the chemical ingredients in Chinese herb preparation Shuang‐Huang‐Lian oral liquid by ultra‐performance liquid chromatography–quadrupole time‐of‐flight mass spectrometry

A target and nontarget strategy based on in‐house chemical components library was developed for rapid and comprehensive analysis of complicated components from traditional Chinese medicine preparation Shuang‐Huang‐Lian oral liquid. The sample was analyzed by ultra‐performance liquid chromatography–quadrupole time‐of‐flight mass spectrometry using generic acquisition parameters. Automated detection and data filtering were performed on the UNIFI™ software and the detected peaks were evaluated against an in‐house library. As a result, a total of 170 chemical components (110 target compounds and 60 nontarget ones) were identified or tentatively characterized, including 54 flavonoids, 30 phenylethanoid glycosides, 16 iridoid glycosides, 14 lignans, 32 organic acids, 19 triterpenoid saponins and five other types of compounds. Among them, 44 compounds were further confirmed by comparison with reference standards. It was demonstrated that this systematical approach could be successfully applied for rapid identification of multiple compounds in traditional Chinese medicine and its preparations. Furthermore, this work established the foundation for the further investigation on the metabolic fates of multiple ingredients in Shuang‐Huang‐Lian oral liquid.     

本刊英文版Vol.30(2014),No.7论文摘要(英文)

<正>Perturbations of Frames Dong Yang CHEN;;Lei LI;;Ben Tuo ZHENG Abstract In this paper,we give some sufficient conditions under which perturbations preserve Hilbert frames and near-Riesz bases.Similar results are also extended to frame sequences,Riesz sequences and Schauder frames.It is worth mentioning that some of our perturbation conditions are quite different from those used in the previous literatures on this topic.Perturbations of Moore-Penrose Metric Generalized Inverses of Linear Operators in Banach Spaces Hai Feng MA;;Shuang SUN;;Yu Wen WANG;;Wen Jing ZHENG