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1.
Fei Cheng Zhen-Xing Zou Ping-Sheng Xu Shui-Han Zhang Yan Zhang Cai-Ping Yao 《Natural product research》2020,34(9):1264-1269
AbstractThree new neolignan derivatives (1–3), together with three known isolariciresinol derivatives (4–6) were isolated from Selaginella picta. Their structures were elucidated by spectroscopic methods (1D/2D NMR, HRESIMS and CD). All isolated compounds were assayed on the neuroprotective activity against the injury of HT-22 cells induced by L-Glutamate in vitro. All compounds displayed potent protective effect on HT-22 cells. 相似文献
2.
Yue‐Hu Wang Qian‐Yun Sun Fu‐Mei Yang Chun‐Lin Long Fu‐Wei Zhao Gui‐Hua Tang Hong‐Mei Niu Huan Wang Qiao‐Qin Huang Jin‐Jin Xu Li‐Juan Ma 《Helvetica chimica acta》2010,93(12):2467-2477
Ten new phenolic compounds including the six neolignans 1 – 3 and 6 – 8 and four caffeoyl derivatives, i.e., myo‐inositol 1‐caffeate ( 9 ), myo‐inositol 6‐caffeate ( 10 ), myo‐inositol 5‐caffeate ( 11 ), and paucine 3′‐β‐D ‐glucopyranoside ( 12 ) were isolated from the whole plants of Selaginella moellendorffii (caffeic acid=3‐(3,4‐dihydroxyphenyl)prop‐2‐enoic acid). Their structures were established by spectroscopic and chemical methods. 相似文献
3.
Yuan Cao Ji‐Jun Chen Ning‐Hua Tan Yong‐Ping Wu Jie Yang Qiang Wang 《Magnetic resonance in chemistry : MRC》2010,48(8):656-659
Selaginellins G ( 1 ) and H ( 2 ), two new selaginellin derivatives, were isolated from the whole plant of Selaginella pulvinata. Their structures were elucidated, and complete assignments of the 1H and 13C NMR spectroscopic data were achieved by 1D and 2D NMR experiments (HSQC, HMBC, COSY and ROESY). Compound 1 displayed good antifungal activity against Candida albicans with an IC50 value of 5.3 µg/ml. Copyright © 2010 John Wiley & Sons, Ltd. 相似文献
4.
《中国化学》2017,35(7):1117-1124
Gout is a disease of purine metabolic disorders which results from long‐term hyperuricemia and the sodium urate deposition in and around the joints. Selaginella tamariscina (ST ) is an important traditional Chinese herbal medicine and is used for the treatment of gout and hyperuricemia. In this study, the rat model of acute gout with hyperuricemia was established by intraperitoneal injection of xanthine and oxonic acid potassium salt and articular injection monosodium urate (MSU ). The effect of ST in the treatment of gout was investigated by measuring joint swelling, the expression of IL ‐1β in serum and histological changes of joint by haematoxylin eosin (H&E) staining. Subsequently, urine metabolomics analysis for biomarkers discovery in acute gout with hyperuricemia rats was performed by the ultra‐performance liquid chromatography‐electrospray ionization quadruple time‐of‐flight mass spectrometry (UPLC‐ESI‐QTOF /MS ) combined with chemometric approach. Principal component analysis (PCA ) and orthogonal partial least squares‐discriminant analysis (OPLS‐DA ) were used to detect potential biomarkers. A total of 18 potential biomarkers were identified mainly including tryptophan metabolism; tyrosine metabolism; lysine methylation; pyrimidine metabolism; purine metabolism; TCA cycle and fatty acid metabolisms. This study indicates that ST could efficiently ameliorate the disease of acute gout with hyperuricemia in rats. The related metabolic biomarkers could provide useful information and the metabolic mechanism could be used for further study about the model of acute gout with hyperuricemia in rats. 相似文献
5.
From the ethanol extract of Selaginella moellendorffii Hieron., a new flavone O-glycoside and three known flavone C-glycosides have been isolated and identified as 5-carboxymethyl-4′-hydroxyflavone-7-O-β-D-glucopyranoside 1, 6,8-di-C-β-D-glueopyranosylapigenin 2, 6-C-[3-D-glucopyranosyl-8-C-β-D-xylopyranosyl apigenin 3, 6-C-B-D-xylopyranosyl-8-C-β-glucopyranosylapigenin 4, respectively. Their structures were elucidated by spectroscopic methods. 相似文献
6.
Xiao Ke Zheng Ke Ke Li Yan Zhi Wang Wei Sheng Feng 《中国化学快报》2008,19(1):79-81
A new lignanoside, (7R,8S)-7,8-dihydro-7-(4-hydroxy-3,5-dimethoxyphenyl)-1'-formyl-3'-y-methoxyl-8-hydroxymethylbenzo- furan-4-O-β-D-glucopyranoside (moellenoside A), was isolated from Selaginella moellendorffii Hieron. Its structure was determined by spectroscopic evidences. 2007 Wei Sheng Feng. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved. 相似文献
7.
采用分光光度法 ,测定了蒙药卷柏中总黄酮的含量 ,检测波长为 5 0 0 nm,校准曲线相关系数为 0 .9996 ,相对标准偏差为 1 .0 1 %,平均加样回收率为 1 0 1 .6 1 %。此法准确度较高 ,为卷柏中黄酮含量测定提供了一种切实可行的方法。 相似文献
8.
A new biflavonoid,2,3-dihydro-5,5″,7,7″,4′-pentahydroxy-6,6″-dimethyl-[3′-O-4′″]-biflavone 1 and two known biflavonoids 2,3″-dihydroochnaflavone 2 and 2″,3″-dihydro-3′,3′″-biapigenin 3 were isolated from the herb of Selaginella labordei Hieron.ex Christ.Their structures were elucidated by spectroscopic methods. 相似文献
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10.
A new sesquilignan from Selaginella sinensis (Desv.) Spring 总被引:1,自引:0,他引:1
Yan Zhi Wang Hui Chen Xiao Ke Zheng Wei Sheng Feng 《中国化学快报》2007,18(10):1224-1226
A new sesquilignan, namely sinensiol A, was isolated from the plant of Selaginella sinensis (Desv.) Spring. Its structure was identified on the basis of various spectroscopic data analysis. 相似文献