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From the methanolic extract of the leaves of Planchonella duclitan, 2α,3α,19α,23‐tetrahydroxy‐13,27‐cyclours‐11‐en‐28‐oic acid (1), myrianthic acid (2), 2‐hydroxyursolic acid (3), ursolic acid (4), pomolic acid (5), rotundic acid (6), and jacoumaric acid (7) were isolated, and their structures were elucidated on the basis of their spectroscopic analysis. Among them, compound 1 was a new cyclopropyl ursane‐type triterpene acid. Additionally, compounds 4 and 7 showed significant cytotoxicity toward human colorectal carcinoma cell line HT29 and human breast carcinoma cell line MCF‐7 with IC50 values ranging from 5.8 ± 1.4 to 6.5 ± 1.9 μM. 相似文献
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Chemical investigation of the EtOH extract of the leaves of Planchonella obovata resulted in the isolation of four benzophenone glucosides, 1 – 4 , of which three, 2 – 4 , are new chemical entities together with five known flavonol glycosides. Their structures were elucidated by spectroscopic analysis. Among the isolated compounds, iriflophenone 2‐O‐(2,6‐di‐O‐galloyl)‐β‐D ‐glucopyranoside ( 4 ) showed some activity (91.4 and 15.0% inhibition at 100 and 10 μg/ml, resp.) against the α‐glucosidase of Bacillus stearothermophilus. 相似文献
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